1-Deoxymannojirimycin hydrochloride structure
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Common Name | 1-Deoxymannojirimycin hydrochloride | ||
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CAS Number | 73465-43-7 | Molecular Weight | 199.633 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C6H14ClNO4 | Melting Point | 183-185ºC | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of 1-Deoxymannojirimycin hydrochloride1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC50 of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor and inhibits HIV‐1 strains. 1-Deoxymannojirimycin hydrochloride has antiviral activity[1][2]. |
Name | (+)-1-Deoxynojirimycin hydrochloride |
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Synonym | More Synonyms |
Description | 1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC50 of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor and inhibits HIV‐1 strains. 1-Deoxymannojirimycin hydrochloride has antiviral activity[1][2]. |
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Related Catalog | |
Target |
IC50: 20 μM (α1,2-mannosidase I)[1] N-linked glycosylation[2] HIV‐1[2] |
References |
Melting Point | 183-185ºC |
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Molecular Formula | C6H14ClNO4 |
Molecular Weight | 199.633 |
Exact Mass | 199.061142 |
PSA | 92.95000 |
Appearance of Characters | Powder | white to off-white |
Storage condition | 2-8°C |
Water Solubility | H2O: soluble10mg/mL |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H302-H312-H332 |
Precautionary Statements | P280 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn: Harmful; |
Risk Phrases | R20/21/22 |
Safety Phrases | 22-24/25-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Glycosylation of native MHC class Ia molecules is required for recognition by allogeneic cytotoxic T lymphocytes.
Glycobiology 6 , 413-421, (1996) The question whether or not target cell N-linked carbohydrate participates in cytotoxic T lymphocyte (CTL) mediated cytolysis has been in contention for well over a decade. Much of the evidence suppor... |
(2R,3R,4R,5R)-3,4,5-Trihydroxy-2-(hydroxymethyl)piperidinium chloride |
Piperidinium, 3,4,5-trihydroxy-2-(hydroxymethyl)-, chloride, (2R,3R,4R,5R)- (1:1) |
1-deoxymannojirimycin hydrochloride |
(2R,3R,4R,5R)-2-(Hydroxymethyl)piperidine-3,4,5-triol hydrochloride (1:1) |