alpha-methyl-dl-tyrosine methyl ester hydrochloride

Modify Date: 2024-01-03 18:35:19

alpha-methyl-dl-tyrosine methyl ester hydrochloride Structure
alpha-methyl-dl-tyrosine methyl ester hydrochloride structure
Common Name alpha-methyl-dl-tyrosine methyl ester hydrochloride
CAS Number 7361-31-1 Molecular Weight 245.70300
Density N/A Boiling Point 336.4ºC at 760 mmHg
Molecular Formula C11H16ClNO3 Melting Point 192 °C (dec.)(lit.)
MSDS USA Flash Point 157.2ºC

 Use of alpha-methyl-dl-tyrosine methyl ester hydrochloride


α-Methyltyrosine methyl ester hydrochloride is a competitive tyrosine hydroxylase inhibitor that inhibits the conversion of tyrosine to dopamine. α-Methyltyrosine methyl ester hydrochloride can be used as a tool for sympathetic nervous system research[1].

 Names

Name methyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate,hydrochloride
Synonym More Synonyms

  Biological Activity

Description α-Methyltyrosine methyl ester hydrochloride is a competitive tyrosine hydroxylase inhibitor that inhibits the conversion of tyrosine to dopamine. α-Methyltyrosine methyl ester hydrochloride can be used as a tool for sympathetic nervous system research[1].
Related Catalog
References

[1]. G Magnusson, et al. Renal lesions induced by alpha-methyltyrosine methylester and alpha-methyltyrosine. Acta Pharmacol Toxicol (Copenh). 1970;28(6):435-44.

 Chemical & Physical Properties

Boiling Point 336.4ºC at 760 mmHg
Melting Point 192 °C (dec.)(lit.)
Molecular Formula C11H16ClNO3
Molecular Weight 245.70300
Flash Point 157.2ºC
Exact Mass 245.08200
PSA 72.55000
LogP 2.32740
Storage condition −20°C
Water Solubility H2O: 50 mg/mL, clear, faintly yellow

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YP2900000
CHEMICAL NAME :
p-Tyrosine, alpha-methyl-, methyl ester, hydrochloride, (+-)-
CAS REGISTRY NUMBER :
7361-31-1
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H15-N-O3.Cl-H
MOLECULAR WEIGHT :
245.73
WISWESSER LINE NOTATION :
QR D1XZ1&VO1 &GH, -R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 28,227,1974

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS YP2900000
HS Code 2922509090

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

MFCD00012606
EINECS 230-900-0
AMPT
2-Methyl-4-hydroxy-DL-phenylalanine methyl ester hydrochloride