17-N,N-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one

Modify Date: 2024-01-09 19:38:45

17-N,N-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one structure	Common Name	17-N,N-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one
	CAS Number	73671-86-0	Molecular Weight	388.59
	Density	1.051g/cm3	Boiling Point	528.3ºC at 760 mmHg
	Molecular Formula	C₂₄H₄₀N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	209.8ºC

Use of 17-N,N-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one

DMAA is an indirect sympathomimetic amine. DMAA constricts blood vessels and raises blood pressure. DMAA can be used for neurological and cardiovascular disease research[1][2].

Name	(7S,11aR)-N,N-Diethyl-1,4a,6a-trimethyl-2-oxohexadecahydro-1H-ind eno[5,4-f]quinoline-7-carboxamide

Description	DMAA is an indirect sympathomimetic amine. DMAA constricts blood vessels and raises blood pressure. DMAA can be used for neurological and cardiovascular disease research[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Neurological Disease
References	[1]. Rodricks JV, et al. DMAA as a dietary ingredient. JAMA Intern Med. 2013 Apr 8;173(7):594-5. [2]. Richard J Bloomer, et al. 1,3-Dimethylamylamine (DMAA): A Brief History and Review of Anecdotal and Laboratory Findings. J Altern Complement Integr Med. 2018 Dec 28.

Description

DMAA is an indirect sympathomimetic amine. DMAA constricts blood vessels and raises blood pressure. DMAA can be used for neurological and cardiovascular disease research[1][2].

Related Catalog

Research Areas >> Cardiovascular Disease

Research Areas >> Neurological Disease

References

[1]. Rodricks JV, et al. DMAA as a dietary ingredient. JAMA Intern Med. 2013 Apr 8;173(7):594-5.

[2]. Richard J Bloomer, et al. 1,3-Dimethylamylamine (DMAA): A Brief History and Review of Anecdotal and Laboratory Findings. J Altern Complement Integr Med. 2018 Dec 28.

Density	1.051g/cm3
Boiling Point	528.3ºC at 760 mmHg
Molecular Formula	C₂₄H₄₀N₂O₂
Molecular Weight	388.59
Flash Point	209.8ºC
Exact Mass	388.30900
PSA	40.62000
LogP	4.27230
Index of Refraction	1.519

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CL5200000

CHEMICAL NAME :: 5-alpha-4-Azaandrostane-17-beta-carboxamide, N,N-diethyl-4-methyl-3-oxo-

CAS REGISTRY NUMBER :: 73671-86-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C24-H40-N2-O2

MOLECULAR WEIGHT :: 388.66

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 2100 mg/kg

SEX/DURATION :: male 14 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 169,67,1982

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 700 mg/kg

SEX/DURATION :: male 14 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 169,67,1982

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 135 mg/kg

SEX/DURATION :: female 13-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 169,67,1982