Formamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

Modify Date: 2025-09-04 21:28:21

Formamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]- structure	Common Name	Formamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
	CAS Number	7411-12-3	Molecular Weight	385.41000
	Density	1.27g/cm3	Boiling Point	715.8ºC at 760 mmHg
	Molecular Formula	C₂₁H₂₃NO₆	Melting Point	264-267ºC
	MSDS	N/A	Flash Point	386.7ºC

Name	N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]formamide
Synonym	More Synonyms

Density	1.27g/cm3
Boiling Point	715.8ºC at 760 mmHg
Melting Point	264-267ºC
Molecular Formula	C₂₁H₂₃NO₆
Molecular Weight	385.41000
Flash Point	386.7ºC
Exact Mass	385.15300
PSA	83.09000
LogP	3.50830
Index of Refraction	1.591

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GH0794000

CHEMICAL NAME :: Colchicine, N-deacetyl-N-formyl-

CAS REGISTRY NUMBER :: 7411-12-3

BEILSTEIN REFERENCE NO. :: 2824080

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C21-H23-N-O6

MOLECULAR WEIGHT :: 385.45

WISWESSER LINE NOTATION :: L B677 MV&T&J CO1 DO1 EO1 JMVH NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 33,1606,1950

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4400 ug/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea

REFERENCE :: PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,284,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2666 ug/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9200 ug/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea

REFERENCE :: PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,284,1957

HS Code	2924299090

Formic Acid

CAS#:64-18-6

Trimethylcolchi...

CAS#:3476-50-4

Formamide,N-[(7...

CAS#:7411-12-3

Literature: Raffauf et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 3854

diazomethane

CAS#:186581-53-3

Formamide,N-[(7...

CAS#:7411-12-3

Literature: Santavy; Reichstein Helvetica Chimica Acta, 1950 , vol. 33, p. 1606,1625

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Formyldescaetylcolchicine,N

N-deacetyl-N-formylcolchicine

N-Formyldeacetylcolchicine

N-Desacetyl-N-formyl-colchicin

COLCHICINE,N-DEACETYL-N-FORMYL

N-((S)-1,2,3,10-Tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-formamid

Gloriosine

N-formyl-N-deacetylcolchicine

N-Formyldesacetylcolchicine

(S)-7-Formylamino-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-on

N-((S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-formamide

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Formamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Customs

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.