Metsulfuron-methyl

Modify Date: 2025-08-20 14:29:18

Metsulfuron-methyl Structure
Metsulfuron-methyl structure
Common Name Metsulfuron-methyl
CAS Number 74223-64-6 Molecular Weight 381.36400
Density 1.473 g/cm3 Boiling Point 647.2ºC at 760 mmHg
Molecular Formula C14H15N5O6S Melting Point 158°C
MSDS Chinese USA Flash Point 345.2ºC
Symbol GHS09
GHS09
Signal Word Warning

 Use of Metsulfuron-methyl


Metsulfuron-methyl is a systemic sulfonylurea herbicide and has been widely used to control broad-leaved weeds and annual grasses in rice, maize, wheat, and barley. Metsulfuron-methyl has highly efficient herbicidal activity and low mammalian toxicity[1].

 Names

Name metsulfuron methyl
Synonym More Synonyms

 Metsulfuron-methyl Biological Activity

Description Metsulfuron-methyl is a systemic sulfonylurea herbicide and has been widely used to control broad-leaved weeds and annual grasses in rice, maize, wheat, and barley. Metsulfuron-methyl has highly efficient herbicidal activity and low mammalian toxicity[1].
Related Catalog
References

[1]. Guangyang Liu, et al. Visual and Colorimetric Sensing of Metsulfuron-Methyl by Exploiting Hydrogen Bond-Induced Anti-Aggregation of Gold Nanoparticles in the Presence of Melamine. Sensors (Basel). 2018 May 17;18(5):1595.

 Chemical & Physical Properties

Density 1.473 g/cm3
Boiling Point 647.2ºC at 760 mmHg
Melting Point 158°C
Molecular Formula C14H15N5O6S
Molecular Weight 381.36400
Flash Point 345.2ºC
Exact Mass 381.07400
PSA 157.85000
LogP 2.03030
Index of Refraction 1.593
Storage condition 0-6°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DH3563000
CHEMICAL NAME :
Benzoic acid, 2-(((((4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino)ca rbonyl)amino)sulfonyl )-, methyl ester
CAS REGISTRY NUMBER :
74223-64-6
BEILSTEIN REFERENCE NO. :
0587472
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C14-H15-N5-O6-S
MOLECULAR WEIGHT :
381.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A669,1984
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A669,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 19,S147,1994
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C16,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>2510 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A669,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
40950 mg/kg/13W-C
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Metabolism (Intermediary) - other proteins
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 19,S147,1994

 Safety Information

Symbol GHS09
GHS09
Signal Word Warning
Hazard Statements H410
Precautionary Statements P273-P391-P501
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes N:Dangerousfortheenvironment;
Risk Phrases R50/53
Safety Phrases S60-S61
RIDADR UN3077 9/PG 3
RTECS DH3563000
HS Code 2935009011

 Customs

HS Code 2935009011
Summary 2935009011 2-chloro-n-((4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl)benzenesulfonamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%

 Articles26

More Articles
Inheritance and molecular characterization of broad range tolerance to herbicides targeting acetohydroxyacid synthase in sunflower.

Theor. Appl. Genet. 124(2) , 355-64, (2012)

Ahasl1 is a multilallelic locus where all the induced and natural mutations for herbicide tolerance were described thus far in sunflower (Helianthus annuus L.). The allele Ahasl1-1 confers moderate to...

Effects of repeated pulsed herbicide exposures on the growth of aquatic macrophytes.

Environ. Toxicol. Chem. 32(1) , 193-200, (2013)

Many contaminants are released into aquatic systems intermittently in a series of pulses. Pulse timing and magnitude can vary according to usage, compound-specific physicochemical properties, and use ...

Cloud point extraction with Triton X-114 for separation of metsulfuron-methyl, chlorsulfuron, and bensulfuron-methyl from water, soil, and rice and analysis by high-performance liquid chromatography.

Arch. Environ. Contam. Toxicol. 61(3) , 359-67, (2011)

A new and efficient analytic methodology based on cloud point extraction (CPE) was developed for determination of pesticide residues of metsulfuron-methyl (MSM), chlorsulfuron (CS), and bensulfuron-me...

 Synonyms

methyl 2-(4-methoxy-6-methyl-1,3,5-triazin-2-ylcarbamoylsulfamoyl)benzoate
Metsulfuron methyl
metsulfuron-methyl
MFCD00128061
methyl 2-[[[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]amino]sulfonyl]benzoate
methyl 2-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate
2-[[[[(4-Methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]amino]sulfonyl]benzoic acid methyl ester
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