1,3-THIAZOLIN-4-ONE-2-ACETONITRILE

Modify Date: 2024-01-02 18:04:10

1,3-THIAZOLIN-4-ONE-2-ACETONITRILE Structure
1,3-THIAZOLIN-4-ONE-2-ACETONITRILE structure
Common Name 1,3-THIAZOLIN-4-ONE-2-ACETONITRILE
CAS Number 74246-64-3 Molecular Weight 140.16300
Density 1.43g/cm3 Boiling Point 300.6ºC at 760 mmHg
Molecular Formula C5H4N2OS Melting Point 183-185ºC
MSDS N/A Flash Point 135.6ºC

 Names

Name 2-(4-oxo-1,3-thiazol-2-yl)acetonitrile
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.43g/cm3
Boiling Point 300.6ºC at 760 mmHg
Melting Point 183-185ºC
Molecular Formula C5H4N2OS
Molecular Weight 140.16300
Flash Point 135.6ºC
Exact Mass 140.00400
PSA 78.52000
LogP 0.00758
Index of Refraction 1.675

 MSDS

Name: 2-(4-oxo-4 5-dihydro-1 3-thiazol-2-yl)acetonitrile 97% Material Safety Data Sheet
Synonym: 1,3-Thiazolin-4-one-2-acetonitril
CAS: 74246-64-3
Section 1 - Chemical Product MSDS Name:2-(4-oxo-4 5-dihydro-1 3-thiazol-2-yl)acetonitrile 97% Material Safety Data Sheet
Synonym:1,3-Thiazolin-4-one-2-acetonitril

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
74246-64-3 2-(4-Oxo-4,5-dihydro-1,3-thiazol-2-yl) 97% unlisted
Hazard Symbols: XN
Risk Phrases: 20/21/22

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Harmful if inhaled. May cause respiratory tract irritation.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 74246-64-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: brown
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 185 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C5H4N2OS
Molecular Weight: 140

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Bases, oxidizing agents, reducing agents, amines.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 74246-64-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2-(4-Oxo-4,5-dihydro-1,3-thiazol-2-yl)acetonitrile - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: NITRILES, SOLID, TOXIC, N.O.S.*
Hazard Class: 6.1
UN Number: 3276
Packing Group: III
IMO
Shipping Name: NITRILES, TOXIC, N.O.S.
Hazard Class: 6.1
UN Number: 3276
Packing Group: III
RID/ADR
Shipping Name: NITRILES, TOXIC, N.O.S.
Hazard Class: 6.1
UN Number: 3276
Packing group: III

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
WGK (Water Danger/Protection)
CAS# 74246-64-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 74246-64-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 74246-64-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xn:Harmful;
Risk Phrases 23/24/25
Safety Phrases S36/37
RIDADR UN 3439
HS Code 2934100090

 Synthetic Route

~88%

1,3-THIAZOLIN-4-ONE-2-ACETONITRILE Structure

1,3-THIAZOLIN-4...

CAS#:74246-64-3

Literature: Shams, Hoda Z.; Khalifa, Fathy A.; Barsoum, Barsoum N.; Naoum, Magdi M. Bulletin de la Societe Chimique de France, 1989 , # 1 p. 119 - 122

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

2-cyanomethyl-2-thiazolin-4-one
2-cyanomethylthiazolidin-4-one
CL 842
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