mercury(II) cation

MOLECULAR FORMULA :

Hg

MOLECULAR WEIGHT :

200.59

WISWESSER LINE NOTATION :

HG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

254 mg/kg

TOXIC EFFECTS :

Skin and Appendages - dermatitis, other (after systemic exposure)

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

43 mg/kg

TOXIC EFFECTS :

Behavioral - tremor Liver - jaundice, other or unclassified Liver - other changes

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

44300 ug/m3/8H

TOXIC EFFECTS :

Behavioral - muscle weakness Liver - other changes Nutritional and Gross Metabolic - body temperature increase

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Human - woman

DOSE/DURATION :

150 ug/m3/46D

TOXIC EFFECTS :

Behavioral - wakefulness Behavioral - anorexia (human) Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

129 mg/kg/5H-C

TOXIC EFFECTS :

Sense Organs and Special Senses (Ear) - tinnitus Behavioral - headache Skin and Appendages - dermatitis, allergic (after systemic exposure)

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

571 uL/kg

TOXIC EFFECTS :

Peripheral Nerve and Sensation - paresthesis Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - sweating

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

29 mg/m3/30H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1 mg/m3/24H/5W-C

TOXIC EFFECTS :

Kidney, Ureter, Bladder - proteinuria

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

8 ug/m3/6.5H/41W-I

TOXIC EFFECTS :

Behavioral - alteration of classical conditioning

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

17 mg/m3/2H/30D-C

TOXIC EFFECTS :

Brain and Coverings - other degenerative changes Behavioral - alteration of classical conditioning Behavioral - alteration of operant conditioning

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

400 mg/kg/14D-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

DOSE :

890 ng/m3/24H

SEX/DURATION :

male 16 week(s) pre-mating

TOXIC EFFECTS :

Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

DOSE :

7440 ng/m3/24H

SEX/DURATION :

male 16 week(s) pre-mating

TOXIC EFFECTS :

Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

DOSE :

1 mg/m3/24H

SEX/DURATION :

female 1-20 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TEST SYSTEM :

Human - man

REFERENCE :

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Tevfik Cenqiz, Ankara Universitesi Tip Fakultesi Mikrobiyoloji Ana Bilim Dah, Ankara, Turkey) V.1- 1967- Volume(issue)/page/year: 9,321,1975 TOXICOLOGY REVIEW STEVA8 Science of the Total Environment. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1972- Volume(issue)/page/year: 2,341,1974 TOXICOLOGY REVIEW ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 13,36,1977 TOXICOLOGY REVIEW 85CVA2 "Oncology 1970, Proceedings of the Tenth International Cancer Congress," Chicago, Year Book Medical Pub., 1971 Volume(issue)/page/year: 5,63,1970 TOXICOLOGY REVIEW JOCMA7 Journal of Occupational Medicine. (Chicago, IL) V.1-9, 1957-67. For publisher information, see:JJOMDZ Volume(issue)/page/year: 2,337,1960 TOXICOLOGY REVIEW PEXTAR Progress in Experimental Tumor Research. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1960- Volume(issue)/page/year: 12,102,1969 TOXICOLOGY REVIEW PDTNBH Paediatrician. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1972- Volume(issue)/page/year: 6,204,1977 TOXICOLOGY REVIEW 49DXAV "Health Evaluation of Heavy Metals in Infant Formula and Junior Food, Proceedings of the Symposium, 1981," Schmidt, E.H.F., and A.G. Hildebrandt, eds., Berlin, Springer-Verlag, 1983 Volume(issue)/page/year: -,57,1983 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Gen Indu):CL 0.1 mg/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.1 mg(Hg)/m3 , vapor (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):CL 0.1 mg/m3,vapor (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.1 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.05 mg/m3 JAN 1993 OEL-AUSTRALIA:TWA 0.1 mg/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.1 mg/m3;Skin JAN 1993 OEL-FINLAND:TWA 0.05 mg/m3 JAN 1993 OEL-FRANCE:TWA 0.05 mg/m3;Skin (vapor) JAN 1993 OEL-FRANCE:TWA 0.1 mg/m3;Skin JAN 1993 OEL-HUNGARY:TWA 0.02 mg/m3;STEL 0.04 mg/m3 JAN 1993 OEL-POLAND:TWA 0.05 mg/m3 JAN 1993 OEL-SWEDEN:TWA 0.05 mg/m3 (vapor) JAN 1993 OEL-SWITZERLAND:TWA 0.005 ppm (0.05 mg/m3);Skin (vapor) JAN 1993 OEL-SWITZERLAND:TWA 0.01 mg/m3;Skin JAN 1993 OEL-TURKEY:TWA 0.1 mg/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MERCURY, ARYL AND INORGANIC-air:CL 0.1 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MERCURY, vapor (as Hg)-air:10H TWA 0.05 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 44870 No. of Facilities: 2072 (estimated) No. of Industries: 32 No. of Occupations: 36 No. of Employees: 15002 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 44870 No. of Facilities: 2937 (estimated) No. of Industries: 42 No. of Occupations: 67 No. of Employees: 71932 (estimated) No. of Female Employees: 23826 (estimated)