1,3'-Dimethylguanosine

Modify Date: 2025-09-10 10:01:58

1,3'-Dimethylguanosine Structure
1,3'-Dimethylguanosine structure
Common Name 1,3'-Dimethylguanosine
CAS Number 74466-66-3 Molecular Weight 311.29
Density N/A Boiling Point N/A
Molecular Formula C12H17N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,3'-Dimethylguanosine


1,3'-Dimethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1,3'-Dimethylguanosine

 1,3'-Dimethylguanosine Biological Activity

Description 1,3'-Dimethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C12H17N5O5
Molecular Weight 311.29
Exact Mass 311.12300
PSA 137.65000
InChIKey FKWCSDZDAGWXEN-IOSLPCCCSA-N
SMILES COC1C(CO)OC(n2cnc3c(=O)n(C)c(N)nc32)C1O
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