Cloricromenehydrochloride
Cloricromenehydrochloride structure
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Common Name | Cloricromenehydrochloride | ||
|---|---|---|---|---|
| CAS Number | 74697-28-2 | Molecular Weight | 432.33800 | |
| Density | N/A | Boiling Point | 538ºC at 760 mmHg | |
| Molecular Formula | C20H27Cl2NO5 | Melting Point | 221-222.3ºC | |
| MSDS | USA | Flash Point | 279.2ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of CloricromenehydrochlorideCloricromen (Cloricromene) hydrochloride is a platelet aggregation inhibitor. Cloricromen hydrochloride can inhibit platelet aggregation in man and in experimental thrombosis[1]. |
| Name | ethyl 2-[8-chloro-3-[2-(diethylamino)ethyl]-4-methyl-2-oxochromen-7-yl]oxyacetate,hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Cloricromen (Cloricromene) hydrochloride is a platelet aggregation inhibitor. Cloricromen hydrochloride can inhibit platelet aggregation in man and in experimental thrombosis[1]. |
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| Related Catalog | |
| References |
| Boiling Point | 538ºC at 760 mmHg |
|---|---|
| Melting Point | 221-222.3ºC |
| Molecular Formula | C20H27Cl2NO5 |
| Molecular Weight | 432.33800 |
| Flash Point | 279.2ºC |
| Exact Mass | 431.12700 |
| PSA | 68.98000 |
| LogP | 4.38300 |
| InChIKey | CCCZJRFQJNGCCU-UHFFFAOYSA-N |
| SMILES | CCOC(=O)COc1ccc2c(C)c(CCN(CC)CC)c(=O)oc2c1Cl.Cl |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | 22 |
| RIDADR | NONH for all modes of transport |
| RTECS | AF8970000 |
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Cloricromene in endotoxemia: role of NF-kappaB.
Naunyn Schmiedebergs Arch. Pharmacol. 370(2) , 140-5, (2004) In this study we investigated, for the first time in vivo, the effect of cloricromene, a cumarine derivative, on NF-kappaB activation in endotoxin-treated rats. Endotoxemia was induced in male rats by... |
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Tumor necrosis factor induces E-selectin production in splanchnic artery occlusion shock.
Am. J. Physiol. 268(4 Pt 2) , H1412-7, (1995) Splanchnic arteries were clamped for 45 min to induce splanchnic artery occlusion (SAO) shock in anesthetized rats. Sham-operated animals were used as controls. Survival time, serum tumor necrosis fac... |
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Preparation and characterization of eudragit retard nanosuspensions for the ocular delivery of cloricromene.
AAPS PharmSciTech 7(1) , E27, (2006) The purpose of this study was to improve the stability of cloricromene (AD6) in ophthalmic formulations and its drug availability at the ocular level. To this end, AD6-loaded polymeric nanoparticle su... |
| AD6 |
| Cloricromen hydrochloride |
| Proendotel (TN) |
| 8-Chloro-3-(2-diethylaminoethyl)-7-ethoxycarbonylmethoxy-4-methylcoumarin hydrochloride |
| Cloricromen hydrohloride |