4-Amidinophenylmethanesulfonyl fluoride hydrochloride

Modify Date: 2025-08-25 11:37:07

4-Amidinophenylmethanesulfonyl fluoride hydrochloride Structure
4-Amidinophenylmethanesulfonyl fluoride hydrochloride structure
Common Name 4-Amidinophenylmethanesulfonyl fluoride hydrochloride
CAS Number 74938-88-8 Molecular Weight 252.69
Density N/A Boiling Point 405.2ºC at 760 mmHg
Molecular Formula C8H10ClFN2O2S Melting Point ~205 °C (dec.)
MSDS USA Flash Point 198.8ºC

 Use of 4-Amidinophenylmethanesulfonyl fluoride hydrochloride


p-APMSF is an irreversible inhibitor of serinase. p-APMSFhas substrate specificity for positively charged side chains of amino acids,lysine, or arginine. p-APMSF can be used to study the irreversible inhibitionof trypsin and thrombin [1].

 Names

Name 4-Amidinophenylmethanesulfonyl fluoride hydrochloride
Synonym More Synonyms

  Biological Activity

Description p-APMSF is an irreversible inhibitor of serinase. p-APMSFhas substrate specificity for positively charged side chains of amino acids,lysine, or arginine. p-APMSF can be used to study the irreversible inhibitionof trypsin and thrombin [1].
Related Catalog
References

[1]. LauraR, et al. (p-Amidinophenyl)methanesulfonyl fluoride, an irreversible inhibitorof serine proteases. Biochemistry. 1980 Oct 14;19(21):4859-64.  

 Chemical & Physical Properties

Boiling Point 405.2ºC at 760 mmHg
Melting Point ~205 °C (dec.)
Molecular Formula C8H10ClFN2O2S
Molecular Weight 252.69
Flash Point 198.8ºC
Exact Mass 252.013550
PSA 92.39000
LogP 3.45280
Storage condition −20°C
Water Solubility H2O: 50 mM Stable when aliquoted at −20°C. Half-life = 6 minutes in pH 7.0 buffer systems.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Risk Phrases 20/21/22-36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2925290090

 Customs

HS Code 2925290090
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles8

More Articles
In vivo pharmacological characterization of TAK-063, a potent and selective phosphodiesterase 10A inhibitor with antipsychotic-like activity in rodents.

J. Pharmacol. Exp. Ther. 352(3) , 471-9, (2015)

Phosphodiesterase 10A (PDE10A) is a cAMP/cGMP phosphodiesterase highly expressed in medium spiny neurons (MSNs) in the striatum. We evaluated the in vivo pharmacological profile of a potent and select...

Zinc binding activity of human metapneumovirus M2-1 protein is indispensable for viral replication and pathogenesis in vivo.

J. Virol. 89 , 6391-405, (2015)

Human metapneumovirus (hMPV) is a member of the Pneumovirinae subfamily in the Paramyxoviridae family that causes respiratory tract infections in humans. Unlike members of the Paramyxovirinae subfamil...

APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription.

FEBS Lett. 589(4) , 532-9, (2015)

APPL1 is a multifunctional endocytic adaptor which acts at different steps of various signaling pathways. Here we report that APPL1 interacts with Dvl2, a protein known to activate the canonical and n...

 Synonyms

(4-Carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride
(4-Carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride (1:1)
Benzenemethanesulfonyl fluoride, 4-(aminoiminomethyl)-, hydrochloride (1:1)
(4-carbamimidoylphenyl)methanesulfonyl fluoride,hydrochloride
MFCD00036898
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here



Get all suppliers and price by the below link:

4-Amidinophenylmethanesulfonyl fluoride hydrochloride suppliers

4-Amidinophenylmethanesulfonyl fluoride hydrochloride price