Bromotrichloromethane

Modify Date: 2025-08-26 16:59:14

Bromotrichloromethane Structure
Bromotrichloromethane structure
Common Name Bromotrichloromethane
CAS Number 75-62-7 Molecular Weight 198.27400
Density 2.012 g/mL at 25 °C(lit.) Boiling Point 105 °C(lit.)
Molecular Formula CBrCl3 Melting Point −6 °C(lit.)
MSDS Chinese USA Flash Point 104-105°C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name Bromotrichloromethane
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.012 g/mL at 25 °C(lit.)
Boiling Point 105 °C(lit.)
Melting Point −6 °C(lit.)
Molecular Formula CBrCl3
Molecular Weight 198.27400
Flash Point 104-105°C
Exact Mass 195.82500
LogP 2.70900
Vapour density 6.85 (vs air)
Vapour Pressure 38.4 mm Hg ( 25 °C)
Index of Refraction n20/D 1.5065(lit.)
Water Solubility insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PA5400000
CHEMICAL NAME :
Methane, bromotrichloro-
CAS REGISTRY NUMBER :
75-62-7
BEILSTEIN REFERENCE NO. :
1732543
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C-Br-Cl3
MOLECULAR WEIGHT :
198.27
WISWESSER LINE NOTATION :
GXGGE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
119 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
1 mmol/L
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 11,243,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1152 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 34 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1152 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302 + H312 + H332
Precautionary Statements P280
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R20/21/22;R36/37/38
Safety Phrases S36/37-S36/37/39-S26
RIDADR UN 2810 6.1/PG 2
WGK Germany 3
RTECS PA5400000
Packaging Group III
Hazard Class 6.1
HS Code 29034700

 Synthetic Route

 Customs

HS Code 29034700

 Articles28

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Chronic ethanol consumption is associated with increased protein oxidation and decreased proteolysis in the liver. We tested the hypothesis that even single-dose treatment with ethanol or bromotrichlo...

Suicidal inactivation of haemoproteins by reductive metabolites of halomethanes: a structure-activity relationship study.

Toxicology 100(1-3) , 175-83, (1995)

Human haemoglobin (Hb), methaemalbumin (MHA) or rat liver microsomal cytochrome P-450 (P-450) were incubated anaerobically at microM concentrations with 1 mM carbon tetrachloride (CCl4), trichlorobrom...

Use of rat liver slices for the study of oxidative DNA damage in comparison with isolated rat liver nuclei and HepG2 human hepatoma cells.

Food Chem. Toxicol. 38(5) , 451-8, (2000)

Tissue slices are a useful biological system for lipid peroxidation studies but their use for DNA damage studies is not well characterized. Hence, the present study investigates DNA damage in rat live...

 Synonyms

bromo(trichloro)methane
MFCD00000783
EINECS 200-886-0
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