f 133a

Modify Date: 2026-06-30 20:01:48

f 133a Structure
f 133a structure
Common Name f 133a
CAS Number 75-88-7 Molecular Weight 118.485
Density 1.3±0.1 g/cm3 Boiling Point 6.9±0.0 °C at 760 mmHg
Molecular Formula C2H2ClF3 Melting Point -105°C
MSDS N/A Flash Point -30.2±10.4 °C

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2-chloro-1,1,1-trifluoroethane
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.3±0.1 g/cm3
Boiling Point 6.9±0.0 °C at 760 mmHg
Melting Point -105°C
Molecular Formula C2H2ClF3
Molecular Weight 118.485
Flash Point -30.2±10.4 °C
Exact Mass 117.979713
LogP 1.11
Vapour Pressure 1431.2±0.0 mmHg at 25°C
Index of Refraction 1.298
InChIKey CYXIKYKBLDZZNW-UHFFFAOYSA-N
SMILES FC(F)(F)CCl

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KH8008500
CHEMICAL NAME :
Ethane, 2-chloro-1,1,1-trifluoro-
CAS REGISTRY NUMBER :
75-88-7
BEILSTEIN REFERENCE NO. :
1733200
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C2-H2-Cl-F3
MOLECULAR WEIGHT :
118.49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
15 pph/1H
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - convulsions or effect on seizure threshold
REFERENCE :
BJANAD British Journal of Anesthesia. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1923- Volume(issue)/page/year: 37,716,1965
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
33000 ppm/5H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530594 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
10 pph/1H/25D-I
TOXIC EFFECTS :
Behavioral - general anesthetic Liver - fatty liver degeneration Kidney, Ureter, Bladder - interstitial nephritis
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0528422 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
78 gm/kg/1Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - testicular tumors Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 72,15,1984 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,253,1986 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,253,1986 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi
Risk Phrases 59
Safety Phrases S9-S23-S59
RIDADR 1983
Hazard Class 2.2
HS Code 2903791013

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2903791013
Summary 2903791013 1-chloro-1,1,2-trifluoroethane。supervision conditions:14abxy。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:5.5%。general tariff:30.0%

 f 133aBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: In-vitro air to blood partition coefficients of the compound, logK(blood) (human/rat)
Source: ChEMBL
Target: N/A
External Id: CHEMBL1798344
Name: In-vitro air to lung partition coefficients of the compound, logK(lung) (human/rat)
Source: ChEMBL
Target: N/A
External Id: CHEMBL1798343
Name: In-vitro blood to lung partition coefficients of the compound, logP(lung) (human/rat)
Source: ChEMBL
Target: N/A
External Id: CHEMBL1798345
Name: Carcinogenesis bioassays from the Carcinogenic Potency Database (CPDB)
Source: 25294
Target: N/A
External Id: cpdb
Name: logBB, log(C brain / C blood)
Source: ChEMBL
Target: N/A
External Id: CHEMBL636006
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

MFCD00039361
f 133a
Chlorotrifluoroethane
2,2,2-Trifluoroethyl chloride
Genetron 133a
Forane 133a
HCFC-133a
1-chloro-2,2,2-trifluoroethane
chloro-1,1,1-trifluoroethane
Ethane,2-chloro-1,1,1-trifluoro
EINECS 200-912-0
2-CHLORO-1,1,1-TRIFLUOROETHANE
1,1,1-TRIFLUORO-2-CHLOROETHANE
chloro-2,2,2-trifluoroethane
(Chloromethyl)trifluoromethane
Freon 133a

 f 133a | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the melting point of 2-chloro-1,1,1-trifluoroethane?
A: Melting point of 2-chloro-1,1,1-trifluoroethane is -105°C.
Q: What is the molecular formula of 2-chloro-1,1,1-trifluoroethane?
A: Molecular formula of 2-chloro-1,1,1-trifluoroethane is C2H2ClF3.
Q: What is the InChIKey of 2-chloro-1,1,1-trifluoroethane?
A: InChIKey of 2-chloro-1,1,1-trifluoroethane is CYXIKYKBLDZZNW-UHFFFAOYSA-N.
Q: What is the safety information for 2-chloro-1,1,1-trifluoroethane?
A: Safety information for 2-chloro-1,1,1-trifluoroethane: S9-S23-S59.
Q: What is the boiling point of 2-chloro-1,1,1-trifluoroethane?
A: Boiling point of 2-chloro-1,1,1-trifluoroethane is 6.9±0.0 °C at 760 mmHg.
Q: What English synonyms does 2-chloro-1,1,1-trifluoroethane have?
A: English synonyms of 2-chloro-1,1,1-trifluoroethane: MFCD00039361, f 133a, Chlorotrifluoroethane, 2,2,2-Trifluoroethyl chloride, Genetron 133a, Forane 133a, HCFC-133a, 1-chloro-2,2,2-trifluoroethane, chloro-1,1,1-trifluoroethane, Ethane,2-chloro-1,1,1-trifluoro, EINECS 200-912-0, 2-CHLORO-1,1,1-TRIFLUOROETHANE, 1,1,1-TRIFLUORO-2-CHLOROETHANE, chloro-2,2,2-trifluoroethane, (Chloromethyl)trifluoromethane, Freon 133a.
Q: What is the English name of 2-chloro-1,1,1-trifluoroethane?
A: The English name of 2-chloro-1,1,1-trifluoroethane is 2-chloro-1,1,1-trifluoroethane.
Q: What is the LogP of 2-chloro-1,1,1-trifluoroethane?
A: LogP of 2-chloro-1,1,1-trifluoroethane is 1.11.
Q: What is the CAS number of 2-chloro-1,1,1-trifluoroethane?
A: CAS number of 2-chloro-1,1,1-trifluoroethane is 75-88-7.
Q: What are the upstream materials of 2-chloro-1,1,1-trifluoroethane?
A: Related upstream materials(CAS) of 2-chloro-1,1,1-trifluoroethane: 79-01-6;1649-08-7;2837-89-0;754-17-6;354-58-5;359-10-4;471-43-2;460-73-1;75-38-7;811-95-0.

 f 133afactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

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