2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Modify Date: 2024-01-31 08:54:57

2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol Structure
2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol structure
 Common Name 2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
CAS Number 75059-23-3 Molecular Weight 339.37
Density 1.78g/cm3 Boiling Point 681.5ºC at 760mmHg
Molecular Formula C13H17N5O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol


8-Allylthioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

 Names

Name 2-(6-amino-8-prop-2-enylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

  Biological Activity

Description 8-Allylthioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

 Chemical & Physical Properties

Density 1.78g/cm3
Boiling Point 681.5ºC at 760mmHg
Molecular Formula C13H17N5O4S
Molecular Weight 339.37
Exact Mass 339.10000
PSA 164.84000
Index of Refraction 1.802
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Chemsrc provides CAS#:75059-23-3 MSDS, density, melting point, boiling point, structure, etc. Its name is 2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol>> amp version: 2-(6-amino-8-prop-2-enylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

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