BI-1124
Modify Date: 2025-08-25 09:02:51
BI-1124 structure
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Common Name | BI-1124 | ||
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| CAS Number | 752237-69-7 | Molecular Weight | 421.586 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H39N5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BI-1124BI-1124 (BI 1124) is a highly potent, selective inhibitor of Cathepsin S (CatS) with IC50 of 7 nM, >40-fold selectivity over Cathepsin L/K/B;BI-1124 had a superior PK profile and showed dose-dependent inhibition of the ovalbumin induced IL-2 secretion in a T cell receptor transgenic DO11 mouse model with an IC50 of 0.3 mg/kg. |
| Name | BI-1124 |
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| Description | BI-1124 (BI 1124) is a highly potent, selective inhibitor of Cathepsin S (CatS) with IC50 of 7 nM, >40-fold selectivity over Cathepsin L/K/B;BI-1124 had a superior PK profile and showed dose-dependent inhibition of the ovalbumin induced IL-2 secretion in a T cell receptor transgenic DO11 mouse model with an IC50 of 0.3 mg/kg. |
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| Molecular Formula | C22H39N5O3 |
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| Molecular Weight | 421.586 |