K6PC-5

Modify Date: 2025-08-25 17:20:57

K6PC-5 structure	Common Name	K6PC-5
	CAS Number	756875-51-1	Molecular Weight	343.50100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₃₇NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of K6PC-5

K6PC-5, a synthetic ceramide derivative,is a direct sphingosine kinase 1(SPHK1) activator and elicites a rapid transient increase in intracellular calcium levels. K6PC-5 is used for the researches of skin diseases involving abnormal keratinocyte, neurodegeneration and virus infection[1][2][3].

Name	N-(1,3-dihydroxypropan-2-yl)-2-hexyl-3-oxodecanamide
Synonym	More Synonyms

Description	K6PC-5, a synthetic ceramide derivative,is a direct sphingosine kinase 1(SPHK1) activator and elicites a rapid transient increase in intracellular calcium levels. K6PC-5 is used for the researches of skin diseases involving abnormal keratinocyte, neurodegeneration and virus infection[1][2][3].
Related Catalog	Research Areas >> Infection Research Areas >> Neurological Disease Signaling Pathways >> Immunology/Inflammation >> SPHK
References	[1]. Kwon YB, et al. Novel synthetic ceramide derivatives increase intracellular calcium levels and promote epidermal keratinocyte differentiation. J Lipid Res. 2007 Sep;48(9):1936-43. [2]. Di Pardo A, et al. Treatment with K6PC-5, a selective stimulator of SPHK1, ameliorates intestinal homeostasis in an animal model of Huntington's disease. Neurobiol Dis. 2020 Sep;143:105009. [3]. Imre G, et al. The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection. iScience. 2021 Mar 5;24(4):102266.

Description

Related Catalog

Research Areas >> Infection

Research Areas >> Neurological Disease

Signaling Pathways >> Immunology/Inflammation >> SPHK

References

[1]. Kwon YB, et al. Novel synthetic ceramide derivatives increase intracellular calcium levels and promote epidermal keratinocyte differentiation. J Lipid Res. 2007 Sep;48(9):1936-43.

[2]. Di Pardo A, et al. Treatment with K6PC-5, a selective stimulator of SPHK1, ameliorates intestinal homeostasis in an animal model of Huntington's disease. Neurobiol Dis. 2020 Sep;143:105009.

[3]. Imre G, et al. The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection. iScience. 2021 Mar 5;24(4):102266.

Molecular Formula	C₁₉H₃₇NO₄
Molecular Weight	343.50100
Exact Mass	343.27200
PSA	90.12000
LogP	3.81230

Hazard Codes	Xi

UNII-9UO46U4GM1

Dihydroxyisopropyl capryloylcaprylamide

K6PC-5

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K6PC-5

Use of K6PC-5

Names

K6PC-5 Biological Activity

Chemical & Physical Properties

Safety Information

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.