2-Methyl-1H-indol-5-amine
2-Methyl-1H-indol-5-amine structure
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Common Name | 2-Methyl-1H-indol-5-amine | ||
|---|---|---|---|---|
| CAS Number | 7570-49-2 | Molecular Weight | 146.189 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 357.3±22.0 °C at 760 mmHg | |
| Molecular Formula | C9H10N2 | Melting Point | 153-157 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 197.1±9.5 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
| Name | 5-Amino-2-methylindole |
|---|---|
| Synonym | More Synonyms |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 357.3±22.0 °C at 760 mmHg |
| Melting Point | 153-157 °C(lit.) |
| Molecular Formula | C9H10N2 |
| Molecular Weight | 146.189 |
| Flash Point | 197.1±9.5 °C |
| Exact Mass | 146.084396 |
| PSA | 41.81000 |
| LogP | 1.16 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.720 |
| InChIKey | JQULCCZIXYRBSE-UHFFFAOYSA-N |
| SMILES | Cc1cc2cc(N)ccc2[nH]1 |
| Storage condition | Freezer |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
~69%
2-Methyl-1H-ind... CAS#:7570-49-2 |
| Literature: Lindsay, David M.; Dohle, Wolfgang; Jensen, Anne Eeg; Kopp, Felix; Knochel, Paul Organic Letters, 2002 , vol. 4, # 11 p. 1819 - 1822 |
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~%
2-Methyl-1H-ind... CAS#:7570-49-2 |
| Literature: Journal of the American Chemical Society, , vol. 77, p. 5375,5376 |
|
~%
2-Methyl-1H-ind... CAS#:7570-49-2 |
| Literature: Organic Letters, , vol. 4, # 11 p. 1819 - 1822 |
|
~%
2-Methyl-1H-ind... CAS#:7570-49-2 |
| Literature: Organic Letters, , vol. 4, # 11 p. 1819 - 1822 |
|
~%
2-Methyl-1H-ind... CAS#:7570-49-2 |
| Literature: Organic Letters, , vol. 4, # 11 p. 1819 - 1822 |
|
~%
2-Methyl-1H-ind... CAS#:7570-49-2 |
| Literature: Journal of Medicinal Chemistry, , vol. 55, # 5 p. 1940 - 1956 |
![2-(2-methoxy-2-propenyl)-N1,N4-di[(E)-phenylmethylidene]-benzene-1,4-diamine structure](https://image.chemsrc.com/caspic/327/438187-37-2.png)
![2-iodo-N1,N4-di[(E)-phenylmethylidene]-benzene-1,4-diamine structure](https://image.chemsrc.com/caspic/403/438187-35-0.png)
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Rational design of novel CYP2A6 inhibitors.
Bioorg. Med. Chem. 22(23) , 6655-64, (2015) Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by e... |
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Name: Solubility of the compound in DMSO at 200 mM
Source: ChEMBL
Target: N/A
External Id: CHEMBL4122989
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Name: Solubility of the compound in aqueous buffer at 1 mM
Source: ChEMBL
Target: N/A
External Id: CHEMBL4122990
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Name: Inhibition of recombinant human N-terminal His6-tagged BRD4 at 20 uM by TR-FRET assay...
Source: ChEMBL
Target: Bromodomain-containing protein 4
External Id: CHEMBL4122987
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Name: Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin ...
Source: ChEMBL
Target: Cytochrome P450 2A6
External Id: CHEMBL3390302
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Name: Binding affinity to recombinant human N-terminal His6-tagged BRD4 bromodomain 1 (44 t...
Source: ChEMBL
Target: Bromodomain-containing protein 4
External Id: CHEMBL4122995
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Name: Binding affinity to Keap1 kelch domain (unknown origin) by surface plasmon resonance ...
Source: ChEMBL
Target: Kelch-like ECH-associated protein 1
External Id: CHEMBL5217617
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Name: Binding affinity to bovine carbonic anhydrase-2 assessed as change in melting tempera...
Source: ChEMBL
Target: Carbonic anhydrase 2
External Id: CHEMBL4122996
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Name: Binding affinity to recombinant human N-terminal His6-tagged BRD4 bromodomain 1 (44 t...
Source: ChEMBL
Target: Bromodomain-containing protein 4
External Id: CHEMBL4122994
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Name: qHTS assay for inhibitors of human lactate dehydrogenase
Source: NCGC
Target: N/A
External Id: LDHA
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Name: Binding affinity to recombinant human N-terminal His6-tagged BRD4 bromodomain 1 (44 t...
Source: ChEMBL
Target: Bromodomain-containing protein 4
External Id: CHEMBL4122991
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| 2-Methyl-1H-indol-5-amine |
| MFCD02093426 |