4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide

Modify Date: 2024-01-03 15:40:20

4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide Structure
4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide structure
 Common Name 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide
CAS Number 757251-39-1 Molecular Weight 261.252
Density 1.3±0.1 g/cm3 Boiling Point 459.8±45.0 °C at 760 mmHg
Molecular Formula C13H12FN3O2 Melting Point 143 °C
MSDS N/A Flash Point 231.9±28.7 °C

 Names

Name 4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 459.8±45.0 °C at 760 mmHg
Melting Point 143 °C
Molecular Formula C13H12FN3O2
Molecular Weight 261.252
Flash Point 231.9±28.7 °C
Exact Mass 261.091370
PSA 77.24000
LogP 0.62
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.602

 Safety Information

Hazard Codes Xi

 Synthetic Route

4-Amino-3-fluorophenol structure

4-Amino-3-fluor...

CAS#:399-95-1

N-Methyl-4-chloropyridine-2-carboxamide structure

N-Methyl-4-chlo...

CAS#:220000-87-3

~74%

4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide Structure

4-(4-amino-3-fl...

CAS#:757251-39-1

Literature: DECIPHERA PHARMACEUTICALS, LLC; FLYNN, Daniel L.; PETILLO, Peter A.; KAUFMAN, Michael D. Patent: WO2013/36232 A2, 2013 ; Location in patent: Paragraph 00220 ;
N-Methyl-4-chloropyridine-2-carboxamide structure

N-Methyl-4-chlo...

CAS#:220000-87-3

~%

4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide Structure

4-(4-amino-3-fl...

CAS#:757251-39-1

Literature: WO2005/9961 A2, ; Page/Page column 46-47 ; WO 2005/009961 A2
3-fluoro-4-((4-methylpentan-2-ylidene)amino)phenol structure

3-fluoro-4-((4-...

CAS#:1338722-52-3

N-Methyl-4-chloropyridine-2-carboxamide structure

N-Methyl-4-chlo...

CAS#:220000-87-3

~%

4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide Structure

4-(4-amino-3-fl...

CAS#:757251-39-1

Literature: WO2011/128261 A1, ; Page/Page column 15-16 ;
3-fluoro-4-((3-methylbutan-2-ylidene)amino)phenol structure

3-fluoro-4-((3-...

CAS#:1338722-53-4

N-Methyl-4-chloropyridine-2-carboxamide structure

N-Methyl-4-chlo...

CAS#:220000-87-3

~%

4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide Structure

4-(4-amino-3-fl...

CAS#:757251-39-1

Literature: WO2011/128261 A1, ; Page/Page column 15-16 ;
4-(cyclohexylideneamino)-3-fluorophenol structure

4-(cyclohexylid...

CAS#:1338722-54-5

N-Methyl-4-chloropyridine-2-carboxamide structure

N-Methyl-4-chlo...

CAS#:220000-87-3

~%

4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide Structure

4-(4-amino-3-fl...

CAS#:757251-39-1

Literature: WO2011/128261 A1, ; Page/Page column 16-17 ;
3-Fluoro-4-nitrophenol structure

3-Fluoro-4-nitr...

CAS#:394-41-2

~%

4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide Structure

4-(4-amino-3-fl...

CAS#:757251-39-1

Literature: WO2011/130728 A1, ; WO 2011/130728 A1
4-Chlorpyridin-2-carbonylchlorid structure

4-Chlorpyridin-...

CAS#:53750-66-6

~%

4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide Structure

4-(4-amino-3-fl...

CAS#:757251-39-1

Literature: WO2013/36232 A2, ;
4-Amino-3-fluorophenol structure

4-Amino-3-fluor...

CAS#:399-95-1

~%

4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide Structure

4-(4-amino-3-fl...

CAS#:757251-39-1

Literature: WO2011/128261 A1, ;

 Synonyms

4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide
2-Pyridinecarboxamide, 4-(4-amino-3-fluorophenoxy)-N-methyl-
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Chemsrc provides CAS#:757251-39-1 MSDS, density, melting point, boiling point, structure, etc. Its name is 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide>> amp version: 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide

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