Substance P-methyl ester

Modify Date: 2025-08-26 19:53:49

Substance P-methyl ester structure	Common Name	Substance P-methyl ester
	CAS Number	76260-78-1	Molecular Weight	1362.64000
	Density	1.41g/cm3	Boiling Point	N/A
	Molecular Formula	C₆₄H₉₉N₁₇O₁₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Substance P-methyl ester

Substance P, [Met-OMet11] is a selective SP-P agonist. Substance P, [Met-OMet11] also is an active peptide. Substance P, [Met-OMet11] can be used for various biochemical studies[1][2].

Name	Substance P-methyl ester
Synonym	More Synonyms

Description	Substance P, [Met-OMet11] is a selective SP-P agonist. Substance P, [Met-OMet11] also is an active peptide. Substance P, [Met-OMet11] can be used for various biochemical studies[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Substance P, [Met-OMet11] (substance P Me ester) 在刺激流涎和回肠收缩方面的效力为 30%[1]。
References	[1]. M A Cascieri, et al. Biological activity of substance P methyl ester. Mol Pharmacol [2]. C M Lee, et al. Multiple tachykinin binding sites in peripheral tissues and in brain. Eur J Pharmacol. 1986 Nov 4;130(3):209-17.

Density	1.41g/cm3
Molecular Formula	C₆₄H₉₉N₁₇O₁₄S
Molecular Weight	1362.64000
Exact Mass	1361.73000
PSA	525.14000
LogP	4.18150
Index of Refraction	1.653

WGK Germany	3

(Nα-Z-Arg1,Nε-Z-Lys3)-SP-OMe structure

(Nα-Z-Arg1,Nε-Z...

CAS#:101914-73-2

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Substance P-methyl ester Structure

Substance P-met...

CAS#:76260-78-1

Literature: Dutta; Gormley; Graham; Briggs; Growcott; Jamieson Journal of Medicinal Chemistry, 1986 , vol. 29, # 7 p. 1163 - 1171

Boc-Gly-OH structure

Boc-Gly-OH

CAS#:4530-20-5

Boc-Leu-OH.H2O structure

Boc-Leu-OH.H2O

CAS#:13139-15-6

Boc-Met-OH structure

Boc-Met-OH

CAS#:2488-15-5

Boc-L-phenylalanine structure

Boc-L-phenylalanine

CAS#:13734-34-4

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Detail

Literature: Fournier; Couture; Regoli; Gendreau; St-Pierre Journal of Medicinal Chemistry, 1982 , vol. 25, # 1 p. 64 - 68

L-Arg-L-Pro-L-Lys-L-Pro-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-OMe

SP methyl ester

SUBSTANCE P METHYL ESTER

Substance P,[Met-OMet11]

H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME

L-Arg-L-Pro-L-Lys-L-Pro-L-Glu(NH2)-L-Glu(NH2)-L-Phe-L-Phe-Gly-L-Leu-L-Met-OMe

Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-OMe,Substance P methyl ester

methylester-substance

substance P-O-methyl ester

ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME

[Met-OMe11]-substance P

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