Dihydrocurcumin

Modify Date: 2024-01-09 15:59:46

Dihydrocurcumin Structure
Dihydrocurcumin structure
Common Name Dihydrocurcumin
CAS Number 76474-56-1 Molecular Weight 370.39600
Density 1.277g/cm3 Boiling Point 616.3ºC at 760 mmHg
Molecular Formula C21H22O6 Melting Point N/A
MSDS N/A Flash Point 217.8ºC

 Use of Dihydrocurcumin


Dihydrocurcumin, a major metabolites of curcumin, reduces lipid accumulation and oxidative stress. Dihydrocurcumin regulates mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, increases protein expression levels of pAKT and PI3K, and reduced the levels of cellular NO and ROS via Nrf2 signaling pathways[1].

 Names

Name (4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-4,6-heptadie n-3-one

 Dihydrocurcumin Biological Activity

Description Dihydrocurcumin, a major metabolites of curcumin, reduces lipid accumulation and oxidative stress. Dihydrocurcumin regulates mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, increases protein expression levels of pAKT and PI3K, and reduced the levels of cellular NO and ROS via Nrf2 signaling pathways[1].
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References

[1]. Yu Q, et al. Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid-induced L02 and HepG2 cells. Biomed Pharmacother. 2018 Jul;103:1327-1336.

 Chemical & Physical Properties

Density 1.277g/cm3
Boiling Point 616.3ºC at 760 mmHg
Molecular Formula C21H22O6
Molecular Weight 370.39600
Flash Point 217.8ºC
Exact Mass 370.14200
PSA 96.22000
LogP 3.77200
Index of Refraction 1.634
Storage condition 2-8℃
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