Ebelactone A

Modify Date: 2025-11-28 13:11:51

Ebelactone A Structure
Ebelactone A structure
Common Name Ebelactone A
CAS Number 76808-16-7 Molecular Weight 338.48200
Density 1.011g/cm3 Boiling Point 462.8ºC at 760 mmHg
Molecular Formula C20H34O4 Melting Point N/A
MSDS USA Flash Point 152.8ºC

 Names

Name ebelactone a
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.011g/cm3
Boiling Point 462.8ºC at 760 mmHg
Molecular Formula C20H34O4
Molecular Weight 338.48200
Flash Point 152.8ºC
Exact Mass 338.24600
PSA 63.60000
LogP 3.76870
Index of Refraction 1.483
InChIKey WOISDAHQBUYEAF-QIQXJRRPSA-N
SMILES CCC(C)C(O)C(C)C(=O)C(C)C=C(C)CC(C)C1OC(=O)C1C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RQ7730000
CHEMICAL NAME :
2-Oxetanone, 4-(8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl) -3-methyl-, (3S-(3- alpha,4-beta(1R*,3E,5S*,7R*,8S*,9S*)))-
CAS REGISTRY NUMBER :
76808-16-7
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H34-O4
MOLECULAR WEIGHT :
338.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 33,1594,1980

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS RQ7730000

 Articles15

More Articles
Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes.

J. Antibiot. 35 , 1495-1499, (1982)

Biosynthetic studies of ebelactone A and B by 13C NMR spectrometry.

J. Antibiot. 35 , 1670, (1982)

Biosynthetic pathways of ebelactone A and B were studied by 13C NMR spectroscopy. By using 13C labeled compounds as precursors it was determined that ebelactone A was derived from one molecule of acet...

Effects of ebelactone B, a lipase inhibitor, on intestinal fat absorption in the rat.

J. Enzym. Inhib. 10(1) , 57-63, (1996)

Ebelactones A and B, natural products from Streptomyces aburaviensis are potent inhibitors of pancreatic lipase. Lipase is the key enzyme required for the absorption of dietary triglycerides (TG). Ebe...

 Synonyms

3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC ACID 1,3-LACTONE
3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECANOIC-1,3-LACTONE
ebelactone a microbial
3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC 1,3-LACTONE
3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECEN-3-OLIDE
3,11-DIHYDROXY-2,4,5,6,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC 1,3-LACTONE
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