Ronidazole

Modify Date: 2024-01-02 15:35:50

Ronidazole structure	Common Name	Ronidazole
	CAS Number	7681-76-7	Molecular Weight	200.152
	Density	1.7±0.1 g/cm3	Boiling Point	502.3±30.0 °C at 760 mmHg
	Molecular Formula	C₆H₈N₄O₄	Melting Point	167-169°
	MSDS	USA	Flash Point	257.6±24.6 °C

Use of Ronidazole

Ronidazole is an antiprotozoal agent.Target: AntiparasiticRonidazole is an antiprotozoal agent used in veterinary medicine. It may also have use for the treatment of Tritrichomonas foetus infection in cats. Ronidazole kills T foetus at concentrations > 0.1 μg/mL in vitro. Ronidazole (30 or 50 mg/kg) cures T foetus infection for follow-up durations of 21 to 30 weeks after treatment in 10/10 cats [1].

Name	(1-methyl-5-nitroimidazol-2-yl)methyl carbamate
Synonym	More Synonyms

Description	Ronidazole is an antiprotozoal agent.Target: AntiparasiticRonidazole is an antiprotozoal agent used in veterinary medicine. It may also have use for the treatment of Tritrichomonas foetus infection in cats. Ronidazole kills T foetus at concentrations > 0.1 μg/mL in vitro. Ronidazole (30 or 50 mg/kg) cures T foetus infection for follow-up durations of 21 to 30 weeks after treatment in 10/10 cats [1].
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection
References	[1]. Lim, S., et al., Efficacy of ronidazole for treatment of cats experimentally infected with a Korean isolate of Tritrichomonas foetus. Korean J Parasitol, 2012. 50(2): p. 161-4.

Density	1.7±0.1 g/cm3
Boiling Point	502.3±30.0 °C at 760 mmHg
Melting Point	167-169°
Molecular Formula	C₆H₈N₄O₄
Molecular Weight	200.152
Flash Point	257.6±24.6 °C
Exact Mass	200.054550
PSA	115.96000
LogP	-0.45
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.651
Storage condition	−20°C

Ronidazole MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI6803000

CHEMICAL NAME :: Imidazole-2-methanol, 1-methyl-5-nitro-, carbamate (ester)

CAS REGISTRY NUMBER :: 7681-76-7

BEILSTEIN REFERENCE NO. :: 0886221

LAST UPDATED :: 199612

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C6-H8-N4-O4

MOLECULAR WEIGHT :: 200.18

WISWESSER LINE NOTATION :: T5N CNJ A1 B1OVZ ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,289,1976

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	NI6803000
HS Code	2933290090

Precursor 0
DownStream 1
CAS#:936-05-0 HMMNI

HS Code	2933290090
Summary	2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Determination of nitroimidazole residues in aquaculture tissue using ultra high performance liquid chromatography coupled to tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 960 , 105-15, (2014)

An UHPLC-MS/MS method was developed for the quantitative confirmatory analysis of residues of nitroimidazole drugs (dimetridazole, ipronidazole, metronidazole, ornidazole and ronidazole) and their cor...

Simultaneous determination of 15 nitroimidazoles in cosmetics by HPLC coupled with electrospray ionization- tandem mass spectrometry.

J. AOAC Int. 97(6) , 1538-45, (2015)

A sensitive and reliable analytical method based on HPLC/MSIMS has been developed for the simultaneous determination of 15 nitroimidazoles in cosmetics. A diversity of cosmetic samples, including powd...

Tritrichomonas foetus infection in cats with diarrhoea in a rescue colony in Italy.

J. Feline Med. Surg. 11(2) , 131-4, (2009)

Faecal samples from 74 cats with chronic large bowel diarrhoea that were living in a rescue colony in Italy, were submitted for assessment of Tritrichomonas foetus by direct microscopy of faecal smear...

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Ronidazole

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EINECS 231-675-1

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Ronidazole
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Ronidazole
Price: ￥298.0/100mg
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

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Ronidazole

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