1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-(acetyloxy)-4-ethyl-, (S)-

Modify Date: 2024-01-04 17:56:46

1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-(acetyloxy)-4-ethyl-, (S)- Structure
1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-(acetyloxy)-4-ethyl-, (S)- structure
Common Name 1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-(acetyloxy)-4-ethyl-, (S)-
CAS Number 7688-64-4 Molecular Weight 390.38900
Density 1.45g/cm3 Boiling Point 741ºC at 760 mmHg
Molecular Formula C22H18N2O5 Melting Point N/A
MSDS N/A Flash Point 401.9ºC

 Names

Name Camptothecin, acetate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.45g/cm3
Boiling Point 741ºC at 760 mmHg
Molecular Formula C22H18N2O5
Molecular Weight 390.38900
Flash Point 401.9ºC
Exact Mass 390.12200
PSA 87.49000
LogP 2.65040
Index of Refraction 1.694

 Synthetic Route

~79%

1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-(acetyloxy)-4-ethyl-, (S)- Structure

1H-Pyrano(3,4:6...

CAS#:7688-64-4

Literature: Kabushiki Kaisha Yakult Honsha Patent: US4473692 A1, 1984 ;

~94%

1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-(acetyloxy)-4-ethyl-, (S)- Structure

1H-Pyrano(3,4:6...

CAS#:7688-64-4

Literature: Nakazawa, Norio; Tagami, Keiko; Iimori, Hitoshi; Sano, Shigeki; Ishikawa, Tsutomu; Nagao, Yoshimitsu Heterocycles, 2001 , vol. 55, # 11 p. 2157 - 2170

~61%

1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-(acetyloxy)-4-ethyl-, (S)- Structure

1H-Pyrano(3,4:6...

CAS#:7688-64-4

Literature: Cao, Zhisong Synthetic Communications, 1997 , vol. 27, # 11 p. 2013 - 2019

~58%

1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-(acetyloxy)-4-ethyl-, (S)- Structure

1H-Pyrano(3,4:6...

CAS#:7688-64-4

Literature: Cao, Zhisong Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 21 p. 2629 - 2632

 Synonyms

(20S)-20-O-Acetylcamptothecin
4-Ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl acetate
camptothecin acetate
(S)-4-acetoxy-4-ethyl-1,12-dihydro-4H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione
20(S)-camptothecin acetate
camptothecin 20(S)-acetate
O-Acetylcamptothecin
20-O-acetylcamptothecin