Zederone
Zederone structure
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Common Name | Zederone | ||
|---|---|---|---|---|
| CAS Number | 7727-79-9 | Molecular Weight | 246.302 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 365.3±42.0 °C at 760 mmHg | |
| Molecular Formula | C15H18O3 | Melting Point | 153.4-153.9℃ (acetone hexane ) | |
| MSDS | N/A | Flash Point | 174.7±27.9 °C | |
Use of ZederoneZederone, a germacrane-type sesquiterpene, has potently cytotoxic against human white blood cancer cells and human prostate cancer cells. Zederone significantly inhibits the proliferation and downregulates the protein expressions of mTOR, and phosphorylated p70 S6 kinase (p-p70s6K) in SKOV3 cells[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Zederone |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Zederone, a germacrane-type sesquiterpene, has potently cytotoxic against human white blood cancer cells and human prostate cancer cells. Zederone significantly inhibits the proliferation and downregulates the protein expressions of mTOR, and phosphorylated p70 S6 kinase (p-p70s6K) in SKOV3 cells[1][2]. |
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| Related Catalog | |
| Target |
mTOR |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 365.3±42.0 °C at 760 mmHg |
| Melting Point | 153.4-153.9℃ (acetone hexane ) |
| Molecular Formula | C15H18O3 |
| Molecular Weight | 246.302 |
| Flash Point | 174.7±27.9 °C |
| Exact Mass | 246.125595 |
| PSA | 42.74000 |
| LogP | 3.58 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.528 |
| InChIKey | CVIVANCKIBYAOP-UHFFFAOYSA-N |
| SMILES | CC1=CCCC2(C)OC2C(=O)c2c(C)coc2C1 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
|---|
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 1a,5,9-Trimethyl-1a,3,6,10a-tetrahydrooxireno[4,5]cyclodeca[1,2-b]furan-10(2H)-one |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What English synonyms does Zederone have? |
| A: English synonyms of Zederone: 1a,5,9-Trimethyl-1a,3,6,10a-tetrahydrooxireno[4,5]cyclodeca[1,2-b]furan-10(2H)-one. |
| Q: What is the molecular formula of Zederone? |
| A: Molecular formula of Zederone is C15H18O3. |
| Q: What is the CAS number of Zederone? |
| A: CAS number of Zederone is 7727-79-9. |
| Q: What is the polar surface area (PSA) of Zederone? |
| A: Polar surface area (PSA) of Zederone is 42.74000. |
| Q: What is the English name of Zederone? |
| A: The English name of Zederone is Zederone. |
| Q: What is the LogP of Zederone? |
| A: LogP of Zederone is 3.58. |
| Q: What is the boiling point of Zederone? |
| A: Boiling point of Zederone is 365.3±42.0 °C at 760 mmHg. |
| Q: What is the InChIKey of Zederone? |
| A: InChIKey of Zederone is CVIVANCKIBYAOP-UHFFFAOYSA-N. |
| Q: What is the SMILES notation of Zederone? |
| A: SMILES notation of Zederone is CC1=CCCC2(C)OC2C(=O)c2c(C)coc2C1. |
| Q: What is the molecular weight of Zederone? |
| A: Molecular weight of Zederone is 246.302. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |