AP-768
Modify Date: 2024-01-12 13:04:42
AP-768 structure
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Common Name | AP-768 | ||
|---|---|---|---|---|
| CAS Number | 780763-95-3 | Molecular Weight | 474.94 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H23ClN4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AP-768CRTh2 antagonist 2 is selective and potent CRTH2 antagonist extracted from patent US20140148470A1, compound Example 1, has an IC50 of ≤10 nM. CRTh2 antagonist 2 can be used in research of androgenic alopecia[1]. |
| Name | CRTh2 antagonist 2 |
|---|
| Description | CRTh2 antagonist 2 is selective and potent CRTH2 antagonist extracted from patent US20140148470A1, compound Example 1, has an IC50 of ≤10 nM. CRTh2 antagonist 2 can be used in research of androgenic alopecia[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: ≤10 nM (CRTh2)[1] |
| In Vitro | CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells) protein, also known as GPR44, is a G-protein coupled receptor (GPCR) which is amongst other ligands most strongly activated by prostaglandin D2 (PGD2). PGD2 is a product of prostaglandin D2 synthase (PTGDS)[1]. |
| References |
[1]. Andreas Schnapp, et al. Pyrimidine compounds for treating hairloss. US20140148470A1. |
| Molecular Formula | C26H23ClN4O3 |
|---|---|
| Molecular Weight | 474.94 |