AP-1/NF-κB activation inhibitor 1
Modify Date: 2025-08-25 10:00:57
AP-1/NF-κB activation inhibitor 1 structure
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Common Name | AP-1/NF-κB activation inhibitor 1 | ||
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| CAS Number | 188936-12-1 | Molecular Weight | 344.25 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H11F3N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AP-1/NF-κB activation inhibitor 1AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor (IC50=1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells[1]. |
| Name | AP-1/NF-κB activation inhibitor 1 |
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| Description | AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor (IC50=1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells[1]. |
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| Molecular Formula | C13H11F3N4O4 |
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| Molecular Weight | 344.25 |
| InChIKey | JWIIKHRJOUQCQG-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1cnc(C(F)(F)F)nc1NN1C(=O)C=C(C)C1=O |