Bermoprofen

Modify Date: 2024-01-09 19:03:16

Bermoprofen structure	Common Name	Bermoprofen
	CAS Number	78499-27-1	Molecular Weight	296.31700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₆O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Bermoprofen

Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory agent. Bermoprofen has potent antipyretic and analgesic activities with a short biological half-life. Bermoprofen is a potent antagonist of LPS-induced fever in rabbits[1][2].

Name	dl-2-(8-methyl-10,11-dihydro-11-oxodibenz[b,f]oxepin-2-yl)propionic acid
Synonym	More Synonyms

Description	Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory agent. Bermoprofen has potent antipyretic and analgesic activities with a short biological half-life. Bermoprofen is a potent antagonist of LPS-induced fever in rabbits[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Bermoprofen (AD-1590) shows ulcerogenic activity as a side-effect like other nonsteroidal anti-inflammatory agents[1].
In Vivo	Bermoprofen (AD-1590) (0.04-0.1 mg/kg; p.o.) shows a dose-related antipyretic activity in LPS-induced febrile rabbits[2]. Animal Model: Male albino rabbits, 2.3-3 kg[2] Dosage: 0.04, 0.4, 0.1 mg/kg Administration: Oral; given 1 h after i.v. injection of LPS Result: Inhibited significantly the rise in rectal temperature at doses of 0.1 mg/kg or more, the temperature returned approximately to normal after 0.4 mg/kg.
References	[1]. Mori M, et al. Prolongation of antipyretic action and reduction of gastric ulcerogenicity in the rat by controlled-release granules of bermoprofen, a new nonsteroidal anti-inflammatory drug. J Pharm Sci. 1991 Sep;80(9):876-80. [2]. Nakamura H, et al. AD-1590, a potent antagonist of lipopolysaccharide-induced fever in rabbits. J Pharm Pharmacol. 1984 Mar;36(3):182-6.

Molecular Formula	C₁₈H₁₆O₄
Molecular Weight	296.31700
Exact Mass	296.10500
PSA	63.60000
LogP	3.71420

2-(8-methyl-10,11-dihydro-11-oxodibenz[b,f]oxepin-2-yl)propionic acid

Bermoprofen

2-(8-Methyl-10,11-dihydro-11-oxodibenz[b,f]oxepin-2-yl)-propionic acid

2-(8-methyl-10,11-dihydro-11-oxodibenz<b,f>oxepin-2-yl)propionic acid

bermoprofen

2-(8-methyl-10,11-dihydro-11-oxodibenz(b,f)oxepin-2-yl)propionic acid

2-(8-Methyl-11-oxo-10,11-dihydro-dibenzo[b,f]oxepin-2-yl)-propionic acid

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: bermoprofen
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

Bermoprofen suppliers

Bermoprofen price

Bermoprofen

Use of Bermoprofen

Names

Bermoprofen Biological Activity

Chemical & Physical Properties

Synonyms