N-Desmethyl Olanzapine-d8

Modify Date: 2024-01-11 18:18:05

N-Desmethyl Olanzapine-d8 Structure
N-Desmethyl Olanzapine-d8 structure
Common Name N-Desmethyl Olanzapine-d8
CAS Number 786686-82-6 Molecular Weight 306.46
Density N/A Boiling Point N/A
Molecular Formula C16H10D8N4S Melting Point 129-131°C (dec.)
MSDS N/A Flash Point N/A

 Use of N-Desmethyl Olanzapine-d8


N-Desmethyl Olanzapine-d8 is deuterium labeled 2-Methyl-4-(piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine.

 Names

Name N-DEMETHYLOLANZAPINE-D8

 N-Desmethyl Olanzapine-d8 Biological Activity

Description N-Desmethyl Olanzapine-d8 is deuterium labeled 2-Methyl-4-(piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Melting Point 129-131°C (dec.)
Molecular Formula C16H10D8N4S
Molecular Weight 306.46
Storage condition -20°C Freezer