MAO-B-IN-27

Modify Date: 2024-01-11 22:27:10

MAO-B-IN-27 Structure
MAO-B-IN-27 structure
Common Name MAO-B-IN-27
CAS Number 788824-83-9 Molecular Weight 331.76
Density N/A Boiling Point N/A
Molecular Formula C16H17ClF3NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MAO-B-IN-27


MAO-B-IN-27 (Compound 12c) is a monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-27 has potent and selective MAO-B inhibitory effect for hMAO-B with an IC50 values of 8.9 nM. MAO-B-IN-27 can be used for the research of parkinson's disease (PD)[1].

 Names

Name MAO-B-IN-27

 MAO-B-IN-27 Biological Activity

Description MAO-B-IN-27 (Compound 12c) is a monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-27 has potent and selective MAO-B inhibitory effect for hMAO-B with an IC50 values of 8.9 nM. MAO-B-IN-27 can be used for the research of parkinson's disease (PD)[1].
Related Catalog
Target

IC50: 8.9 nM (hMAO-B)[1].

References

[1]. Yeon SK, et al. Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy. Bioorg Med Chem. 2018 Jan 1;26(1):232-244.  

 Chemical & Physical Properties

Molecular Formula C16H17ClF3NO
Molecular Weight 331.76
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