Pipecolic acid-d9

Modify Date: 2024-01-27 00:31:52

Pipecolic acid-d9 Structure
Pipecolic acid-d9 structure
Common Name Pipecolic acid-d9
CAS Number 790612-94-1 Molecular Weight 138.21
Density N/A Boiling Point N/A
Molecular Formula C6H2D9NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pipecolic acid-d9


Pipecolic acid-d9 is the deuterium labeled Pipecolic acid. Pipecolic acid, a metabolite of Lysine, is an important precursor of many useful microbial secondary metabolites. Pipecolic acid can be used as a diagnostic marker of Pyridoxine-dependent epilepsy[1][2].

 Names

Name 2,3,3,4,4,5,5,6,6-nonadeuteriopiperidine-2-carboxylic acid
Synonym More Synonyms

 Pipecolic acid-d9 Biological Activity

Description Pipecolic acid-d9 is the deuterium labeled Pipecolic acid. Pipecolic acid, a metabolite of Lysine, is an important precursor of many useful microbial secondary metabolites. Pipecolic acid can be used as a diagnostic marker of Pyridoxine-dependent epilepsy[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. He M, et al. Pipecolic acid in microbes: biosynthetic routes and enzymes. J Ind Microbiol Biotechnol. 2006 Jun;33(6):401-7.

[3]. Plecko B, et, al. Pipecolic acid as a diagnostic marker of pyridoxine-dependent epilepsy. Neuropediatrics. 2005 Jun;36(3):200-5.

 Chemical & Physical Properties

Molecular Formula C6H2D9NO2
Molecular Weight 138.21
Exact Mass 138.13500
PSA 49.33000
LogP 0.54190

 Synonyms

Dihydrobaikiane-d9
Hexahydro-2-picolinic acid
Pipecolinic Acid-d9
Piperolinic Acid-d9
2-Pipecolinic Acid-d9
Pipecolic Acid-d9
|A-Pipecolinic Acid-d9
DL-Pipecolic Acid-d9
2-Carboxypiperidine-d9