DMHAPC-Chol
Modify Date: 2025-09-24 01:21:24
DMHAPC-Chol structure
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Common Name | DMHAPC-Chol | ||
|---|---|---|---|---|
| CAS Number | 794494-38-5 | Molecular Weight | 559.9 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H63N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DMHAPC-CholDMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells. DMHAPC-Chol, as part of a lipoplex with DOPE, has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF. |
| Name | DMHAPC-Chol |
|---|
| Description | DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells. DMHAPC-Chol, as part of a lipoplex with DOPE, has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF. |
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| Molecular Formula | C35H63N2O3 |
|---|---|
| Molecular Weight | 559.9 |
| InChIKey | ZTGXTDBNSSOEDB-SJTWHRLHSA-O |
| SMILES | CC(C)CCCC(C)C1CCC2C3CC=C4CC(OC(=O)NCCC[N+](C)(C)CCO)CCC4(C)C3CCC12C |