794494-38-5
794494-38-5 structure
- Name: DMHAPC-Chol
- Chemical Name: DMHAPC-Chol
- CAS Number: 794494-38-5
- Molecular Formula: C35H63N2O3
- Molecular Weight: 559.9
- Create Date: 2021-01-07 19:58:58
- Modify Date: 2024-02-14 17:11:08
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DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells. DMHAPC-Chol, as part of a lipoplex with DOPE, has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF.
| Name | DMHAPC-Chol |
|---|
| Description | DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells. DMHAPC-Chol, as part of a lipoplex with DOPE, has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF. |
|---|
| Molecular Formula | C35H63N2O3 |
|---|---|
| Molecular Weight | 559.9 |