ACG-548B
Modify Date: 2025-08-31 19:29:18
ACG-548B structure
|
Common Name | ACG-548B | ||
|---|---|---|---|---|
| CAS Number | 795316-16-4 | Molecular Weight | 777.426 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C38H34Br2Cl2N4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ACG-548BA potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM, >400-fold selectivity over ChoKβ; demonstrates in vitro antiproliferative activity against HT29 cells with IC50 of 2.08 uM. |
| Name | ACG-548B |
|---|
| Description | A potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM, >400-fold selectivity over ChoKβ; demonstrates in vitro antiproliferative activity against HT29 cells with IC50 of 2.08 uM. |
|---|---|
| References | References 1. Lacal JC, et al. Mol Cancer Ther. 2015 Jan;14(1):31-9. 2. Patent US 20110178124 A1. Pyridinium and quinolinium derivatives. View Related Products by Target Choline Kinase (ChoK) |
| Molecular Formula | C38H34Br2Cl2N4 |
|---|---|
| Molecular Weight | 777.426 |
| InChIKey | ZFCCRPWNWOHZEN-UHFFFAOYSA-L |
| SMILES | CN(c1ccc(Cl)cc1)c1cc[n+](Cc2cccc(-c3cccc(C[n+]4ccc(N(C)c5ccc(Cl)cc5)cc4)c3)c2)cc1.[Br-].[Br-] |