(1R,2R)-1-(DIPHENYLPHOSPHINO)-1-PHENYLPROPAN-2-AMINE structure
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Common Name | (1R,2R)-1-(DIPHENYLPHOSPHINO)-1-PHENYLPROPAN-2-AMINE | ||
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CAS Number | 799297-44-2 | Molecular Weight | 319.38000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C21H22NP | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
GHS05 |
Signal Word | Danger |
Name | (1R,2R)-1-diphenylphosphanyl-1-phenylpropan-2-amine |
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Synonym | More Synonyms |
Molecular Formula | C21H22NP |
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Molecular Weight | 319.38000 |
Exact Mass | 319.14900 |
PSA | 39.61000 |
LogP | 4.90810 |
Section 1: Product Identification Chemical Name:(1R,2R)-2-Amino-1-phenylpropyldiphenylphosphine, min. 97% CAS Registry Number:799297-44-2 Formula:C21H22NP EINECS Number:none Chemical Family:organophosphine ligand Synonym:(1R,2R)-2-Amino-1-phenylpropyldiphenylphosphane
Section 2: Composition and Information on Ingredients IngredientCAS NumberPercentACGIH (TWA)OSHA (PEL) Title compound799297-44-2100%no datano data Section 3: Hazards Identification Emergency Overview:Irritating to skin, eyes and respiratory tract. May be harmful if swallowed. Primary Routes of Exposure:Ingestion, inhalation Eye Contact:Causes slight to mild irritation of the eyes. Skin Contact:Causes moderate irritation of the skin. Inhalation:Dust is Irritating to the nose, mucous membranes and respiratory tract. Ingestion:No information available on the physiological effects of ingestion. May be harmful if swallowed. Acute Health Affects:Irritating to skin, eyes and respiratory tract. Chronic Health Affects:No information on long-term chronic effects. NTP:No IARC:No OSHA:No SECTION 4: First Aid Measures Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need Eye Exposure: assistance in keeping their eye lids open. Get immediate medical attention. Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if Skin Exposure: irritation persists. Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty Inhalation: in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance. Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce Ingestion: vomiting only if directed by medical personnel. SECTION 5: Fire Fighting Measures Flash Point:no data Autoignition Temperature:no data Explosion Limits:no data Extinguishing Medium:carbon dioxide, dry powder or foam If this product is involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure Special Fire Fighting Procedures: self-contained breathing apparatus and full protective clothing. Hazardous Combustion andIf involved in a fire this material may emit irritating fumes. Decomposion Products: Unusual Fire or Explosion Hazards: No unusual fire or explosion hazards. SECTION 6: Accidental Release Measures Spill and Leak Procedures:Small spills can be mixed with vermiculite or sodium carbonate and swept up. SECTION 7: Handling and Storage Store in a tightly sealed container under an inert atmosphere of nitrogen or argon. Keep in a cool, dry, well Handling and Storage: ventilated place. SECTION 8: Exposure Controls and Personal Protection Eye Protection:Always wear approved safety glasses when handling a chemical substance in the laboratory. Skin Protection:Wear protective clothing and gloves. Ventilation:Handle the material in an efficient fume hood. If ventilation is not available a respirator should be worn. The use of respirators requires a Respirator Respirator: Protection Program to be in compliance with 29 CFR 1910.134. Ventilation:Handle the material in an efficient fume hood. Additional Protection:No additional protection required. SECTION 9: Physical and Chemical Properties Color and Form:white solid Molecular Weight:319.38 Melting Point:no data Boiling Point:no data Vapor Pressure:no data Specific Gravity:no data Odor:none Solubility in Water:Insoluble SECTION 10: Stability and Reactivity Stability:air sensitive Hazardous Polymerization:no hazardous polymerization Conditions to Avoid:prolonged exposure to air Incompatibility:strong oxidizing agents Decomposition Products:carbon monoxide, carbon dioxide, nitrogen oxides, phosphorous oxides and organic fumes SECTION 11: Toxicological Information RTECS Data:No information available in the RTECS files Carcinogenic Effects:No data Mutagenic Effects:No data Tetratogenic Effects:No data SECTION 12: Ecological Information Ecological Information:No information available SECTION 13: Disposal Considerations Disposal:Dispose of according to local, state and federal regulations. SECTION 14: Transportation Shipping Name (CFR):Non-hazardous Hazard Class (CFR):NA Additional Hazard Class (CFR):NA Packaging Group (CFR):NA UN ID Number (CFR):NA Shipping Name (IATA):Non-hazardous Hazard Class (IATA):NA Additional Hazard Class (IATA):NA Packaging Group (IATA):NA UN ID Number (IATA):NA SECTION 15: Regulatory Information TSCA:Not listed in the TSCA inventory SARA (Title 313):Title compound not listed Second Ingredient:none SECTION 16 - ADDITIONAL INFORMATION N/A |
Symbol |
GHS05 |
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Signal Word | Danger |
Hazard Statements | H314 |
Precautionary Statements | P280-P305 + P351 + P338-P310 |
Hazard Codes | C |
RIDADR | UN 3263 8 / PGIII |
Chemoselective hydrogenation of imides catalyzed by Cp*Ru(PN) complexes and its application to the asymmetric synthesis of paroxetine.
J. Am. Chem. Soc. 129 , 290, (2007)
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Hydrogenation of N-acylcarbamates and N-acylsulfonamides catalyzed by a bifunctional [Cp*Ru(PN)] complex.
Angew. Chem. Int. Ed. Engl. 48 , 1324, (2009) Awakening of the Cp one: The bifunctional complex 1 facilitates the interaction with substrates bearing less electrophilic carbon atoms than ketones, epoxides, and imides. The title reaction was appli... |
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D. Amoroso, T.W. Graham et al.
Aldrichimica Acta 41 , 1, 15, (2008)
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MFCD17018768 |