Ethyl α-hydroxyisobutyrate

Modify Date: 2026-07-07 11:57:32

Ethyl α-hydroxyisobutyrate structure	Common Name	Ethyl α-hydroxyisobutyrate
	CAS Number	80-55-7	Molecular Weight	132.158
	Density	1.0±0.1 g/cm3	Boiling Point	152.1±8.0 °C at 760 mmHg
	Molecular Formula	C₆H₁₂O₃	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	44.4±0.0 °C
	Symbol	GHS02, GHS07	Signal Word	Warning

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	Ethyl 2-Hydroxyisobutyrate
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.0±0.1 g/cm3
Boiling Point	152.1±8.0 °C at 760 mmHg
Molecular Formula	C₆H₁₂O₃
Molecular Weight	132.158
Flash Point	44.4±0.0 °C
Exact Mass	132.078644
PSA	46.53000
LogP	0.16
Vapour Pressure	1.3±0.6 mmHg at 25°C
Index of Refraction	1.428
InChIKey	GFUIDHWFLMPAGY-UHFFFAOYSA-N
SMILES	CCOC(=O)C(C)(C)O

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Ethyl α-hydroxyisobutyrate MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OD5672000

CHEMICAL NAME :: Lactic acid, 2-methyl-, ethyl ester

CAS REGISTRY NUMBER :: 80-55-7

BEILSTEIN REFERENCE NO. :: 0878308

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H12-O3

MOLECULAR WEIGHT :: 132.18

WISWESSER LINE NOTATION :: QX1&1&VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 76,189,1942 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7053 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 919 (estimated) No. of Female Employees: 306 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS02, GHS07
Signal Word	Warning
Hazard Statements	H226-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R10;R36/38
Safety Phrases	S26-S36-S16
RIDADR	UN 3272 3/PG 3
WGK Germany	3
RTECS	OD5672000
Packaging Group	III
Hazard Class	3
HS Code	29181980

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

ethyl 2-(methox...

CAS#:1243055-35-7

~83%

Ethyl α-hydroxy...

CAS#:80-55-7

Learn More

Literature: Watanabe, Kohtaro; Andou, Yoshito; Shirai, Yosihito; Nishida, Haruo Chemistry Letters, 2010 , vol. 39, # 7 p. 698 - 699

Ethyl 2-bromois...

CAS#:600-00-0

Formaldehyde

CAS#:50-00-0

~82%

Ethyl α-hydroxy...

CAS#:80-55-7

Learn More

Literature: Soengas, Raquel G.; Estevez, Amalia M. Synlett, 2010 , # 17 p. 2625 - 2627

Ethanol

CAS#:64-17-5

2-Hydroxyisobut...

CAS#:594-61-6

Ethyl α-hydroxy...

CAS#:80-55-7

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Literature: US2029694 , ; US2101821 , ;

H-Aib-Oet.HCl

CAS#:17288-15-2

Ethyl α-hydroxy...

CAS#:80-55-7

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Literature: Journal of the American Chemical Society, , vol. 46, p. 412

2-methyl-2-(10-...

CAS#:24173-45-3

10-METHYLACRIDI...

CAS#:26456-05-3

Ethyl α-hydroxy...

CAS#:80-55-7

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Literature: Journal of the American Chemical Society, , vol. 115, # 20 p. 8960 - 8968

Ethanol

CAS#:64-17-5

Acetone cyanohydrin

CAS#:75-86-5

Ethyl α-hydroxy...

CAS#:80-55-7

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Literature: Zhurnal Obshchei Khimii, , vol. 25, p. 2289;engl.Ausg.S.2257

Diethyloxalate

CAS#:95-92-1

Ethyl α-hydroxy...

CAS#:80-55-7

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Literature: Journal of the Chemical Society, , vol. 115, p. 1207

Ethyl iodide

CAS#:75-03-6

Ethyl α-hydroxy...

CAS#:80-55-7

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Literature: Justus Liebigs Annalen der Chemie, , vol. 188, p. 57

Hydrochloric acid

CAS#:7647-01-0

H-Aib-Oet.HCl

CAS#:17288-15-2

Methacrylic acid

CAS#:79-41-4

Ethyl methacrylate

CAS#:97-63-2

Detail Learn More

Literature: Journal of the American Chemical Society, , vol. 46, p. 412

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:1243055-35-7 ethyl 2-(methox... CAS#:600-00-0 Ethyl 2-bromois... CAS#:50-00-0 Formaldehyde CAS#:64-17-5 Ethanol
CAS#:594-61-6 2-Hydroxyisobut... CAS#:17288-15-2 H-Aib-Oet.HCl CAS#:24173-45-3 2-methyl-2-(10-... CAS#:75-86-5 Acetone cyanohydrin
CAS#:95-92-1 Diethyloxalate CAS#:75-03-6 Ethyl iodide
DownStream 10
CAS#:1068-81-1 2-methylheptane... CAS#:55816-69-8 Ethyl 2-fluoro-... CAS#:97-63-2 Ethyl methacrylate CAS#:605680-62-4 2-METHYL-2-(5-(...
CAS#:18069-17-5 (2R)-2-Methylpe... CAS#:21127-99-1 ethyl 2-methoxy... CAS#:18672-04-3 Ethyl 2-methyl-... CAS#:122-79-2 phenyl acetate
CAS#:79-41-4 Methacrylic acid CAS#:594-61-6 2-Hydroxyisobut...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2918199090
Summary	2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose

Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose

Total 2, Current Page 1 of 1

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester (9CI)

Ethyl α-hydroxyisobutyrate

Ethyl 2-hydroxy-2-methylpropanoate

EINECS 201-290-3

Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester

MFCD00004458

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the boiling point of Ethyl 2-Hydroxyisobutyrate?

A: Boiling point of Ethyl 2-Hydroxyisobutyrate is 152.1±8.0 °C at 760 mmHg.

Q: What are the downstream products of Ethyl 2-Hydroxyisobutyrate?

A: Related downstream products(CAS) of Ethyl 2-Hydroxyisobutyrate: 1068-81-1;55816-69-8;97-63-2;605680-62-4;18069-17-5;21127-99-1;18672-04-3;122-79-2;79-41-4;594-61-6.

Q: What are the upstream materials of Ethyl 2-Hydroxyisobutyrate?

A: Related upstream materials(CAS) of Ethyl 2-Hydroxyisobutyrate: 1243055-35-7;600-00-0;50-00-0;64-17-5;594-61-6;17288-15-2;24173-45-3;75-86-5;95-92-1;75-03-6.

Q: What is the InChIKey of Ethyl 2-Hydroxyisobutyrate?

A: InChIKey of Ethyl 2-Hydroxyisobutyrate is GFUIDHWFLMPAGY-UHFFFAOYSA-N.

Q: What is the SMILES notation of Ethyl 2-Hydroxyisobutyrate?

A: SMILES notation of Ethyl 2-Hydroxyisobutyrate is CCOC(=O)C(C)(C)O.

Q: What is the molecular weight of Ethyl 2-Hydroxyisobutyrate?

A: Molecular weight of Ethyl 2-Hydroxyisobutyrate is 132.158.

Q: What is the molecular formula of Ethyl 2-Hydroxyisobutyrate?

A: Molecular formula of Ethyl 2-Hydroxyisobutyrate is C6H12O3.

Q: What is the English name of Ethyl 2-Hydroxyisobutyrate?

A: The English name of Ethyl 2-Hydroxyisobutyrate is Ethyl 2-Hydroxyisobutyrate.

Q: What is the safety information for Ethyl 2-Hydroxyisobutyrate?

A: Safety information for Ethyl 2-Hydroxyisobutyrate: S26-S36-S16.

Q: What is the CAS number of Ethyl 2-Hydroxyisobutyrate?

A: CAS number of Ethyl 2-Hydroxyisobutyrate is 80-55-7.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Ethyl α-hydroxyisobutyrate
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ethyl 2-hydroxyisobutyrate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Ethyl α-hydroxyisobutyrate

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.