Spiramycin structure
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Common Name | Spiramycin | ||
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CAS Number | 8025-81-8 | Molecular Weight | 843.053 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 913.7±65.0 °C at 760 mmHg | |
Molecular Formula | C43H74N2O14 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 506.4±34.3 °C |
Use of SpiramycinSpiramycin is a clinically important 16-member macrolide antibiotic produced by Streptomyces ambofaciens. |
Name | Spiramycin |
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Synonym | More Synonyms |
Description | Spiramycin is a clinically important 16-member macrolide antibiotic produced by Streptomyces ambofaciens. |
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Related Catalog | |
Target |
Bacterial[1] |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 913.7±65.0 °C at 760 mmHg |
Molecular Formula | C43H74N2O14 |
Molecular Weight | 843.053 |
Flash Point | 506.4±34.3 °C |
Exact Mass | 842.513977 |
LogP | 3.06 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.550 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
Risk Phrases | 36/37/38 |
Safety Phrases | 26-36-24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 1 |
RTECS | WG9400000 |
HS Code | 29419090 |
Regulation of the biosynthesis of the macrolide antibiotic spiramycin in Streptomyces ambofaciens.
J. Bacteriol. 192(21) , 5813-21, (2010) Streptomyces ambofaciens synthesizes the macrolide antibiotic spiramycin. The biosynthetic gene cluster for spiramycin has been characterized for S. ambofaciens. In addition to the regulatory gene srm... |
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A spicamycin derivative (KRN5500) provides neuropathic pain relief in patients with advanced cancer: a placebo-controlled, proof-of-concept trial.
J. Pain Symptom Manage. 43(4) , 679-93, (2012) Neuropathic pain in patients with cancer can be difficult to treat effectively.The purpose of the study was to determine safety and efficacy of KRN5500, a novel, spicamycin-derived, nonopioid analgesi... |
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Influences of two antibiotic contaminants on the production, release and toxicity of microcystins
Ecotoxicol. Environ. Saf. 77 , 79-87, (2012) The influences of spiramycin and amoxicillin on the algal growth, production and release of target microcystins (MCs), MC-LR, MC-RR and MC-YR, in Microcystis aeruginosa were investigated through the s... |
[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2R,5S,6S)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde (non-preferred name) |
Leucomycin |
Foromacidin |
Provamycin |
[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2R,5S,6S)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde |
Spiramycin I |
Rovamycin |