H-Lys-Gln-Ala-Gly-Asp-Val-OH

Modify Date: 2024-01-08 09:47:37

H-Lys-Gln-Ala-Gly-Asp-Val-OH structure	Common Name	H-Lys-Gln-Ala-Gly-Asp-Val-OH
	CAS Number	80755-87-9	Molecular Weight	616.66400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₄₄N₈O₁₀	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of H-Lys-Gln-Ala-Gly-Asp-Val-OH

Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs)[1][2].

Name	2-[[2-[[2-[2-[[5-amino-2-(2,6-diaminohexanoylamino)-5-oxopentanoyl]amino]propanoylamino]acetyl]amino]-3-carboxypropanoyl]amino]-3-methylbutanoic acid
Synonym	More Synonyms

Description	Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs)[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Cytoskeleton >> Integrin
In Vitro	Lys-Gln-Ala-Gly-Asp-Val (2 nM) improves smooth muscle cell adhesion and growth on polymers[2].

Molecular Formula	C₂₅H₄₄N₈O₁₀
Molecular Weight	616.66400
Exact Mass	616.31800
PSA	315.23000
LogP	0.05420

H-Lys-Gln-Ala-Gly-Asp-Val-OH MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3

Evaluation of various silicon-and boron-containing compounds for the detection of phosphorylation in peptides via gas-phase ion-molecule reactions.

Eur. J. Mass Spectrom. (Chichester, Eng.) 20(4) , 337-44, (2014)

Gas-phase ion-molecule reactions [IMR] of various boron- and silicon-containing neutrals were investigated as a potential route for detecting phosphorylation within peptides in the negative ion mode. ...

Cell adhesion peptides alter smooth muscle cell adhesion, proliferation, migration, and matrix protein synthesis on modified surfaces and in polymer scaffolds.

J. Biomed. Mater. Res. 60 , 86-93, (2002)

The effects of cell adhesion peptides (RGDS, KQAGDV, VAPG) on vascular smooth muscle cells grown on modified surfaces and in tissue-engineering scaffolds were examined. Cells were more strongly adhere...

Platelets may inhibit leucotriene biosynthesis by human neutrophils at the integrin level.

Br. J. Haematol. 121 , 341-348, (2003)

Polymorphonuclear leucocytes and blood platelets co-operate in several pathophysiological processes, and arachidonic acid (AA) metabolites produced in response to the activation of these cells are pot...

Lys-Gln-Ala-Gly-Asp-Val

K-Q-A-G-D-V