Spergualin trihydrochloride

Modify Date: 2024-01-14 14:08:59

Spergualin trihydrochloride Structure
Spergualin trihydrochloride structure
Common Name Spergualin trihydrochloride
CAS Number 80952-47-2 Molecular Weight 512.90300
Density N/A Boiling Point N/A
Molecular Formula C17H40Cl3N7O4 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Spergualin trihydrochloride


Spergualin trihydrochloride is a natural product that first identified as an antibiotic from culture filtrates of Bacillus laterosporus BMG162-aF2[1].

 Names

Name (3S)-N-[(1S)-2-[4-(3-aminopropylamino)butylamino]-1-hydroxy-2-oxoethyl]-7-(diaminomethylideneamino)-3-hydroxyheptanamide,trihydrochloride
Synonym More Synonyms

 Spergualin trihydrochloride Biological Activity

Description Spergualin trihydrochloride is a natural product that first identified as an antibiotic from culture filtrates of Bacillus laterosporus BMG162-aF2[1].
Related Catalog
In Vitro Spergualin trihydrochloride derivatives likely acts as Hsp70 modulators[1].
References

[1]. Srikanth Patury, et al. Pharmacological Targeting of the Hsp70 Chaperone. Curr Top Med Chem. 2009;9(15):1337-51.

 Chemical & Physical Properties

Molecular Formula C17H40Cl3N7O4
Molecular Weight 512.90300
Exact Mass 511.22100
PSA 205.59000
LogP 4.02890

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
RIDADR NONH for all modes of transport

 Articles1

More Articles
Improved synthesis of 15-deoxyspergualin analogs using the Ugi multi-component reaction.

Bioorg. Med. Chem. Lett. 21(9) , 2587-90, (2011)

Spergualin is a natural product that exhibits immunosuppressive, anti-tumor and anti-bacterial activities. Its derivatives, such as 15-deoxyspergualin (15-DSG), have been clinically approved for acute...

 Synonyms

Spergualin trihydrochloride
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