n-Butyl β-D-fructofuranoside

Modify Date: 2024-01-11 15:06:48

n-Butyl β-D-fructofuranoside Structure
n-Butyl β-D-fructofuranoside structure
Common Name n-Butyl β-D-fructofuranoside
CAS Number 80971-60-4 Molecular Weight 236.26200
Density N/A Boiling Point N/A
Molecular Formula C10H20O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of n-Butyl β-D-fructofuranoside


n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research[1].

 Names

Name (2R,3S,4S,5R)-2-butoxy-2,5-bis(hydroxymethyl)oxolane-3,4-diol
Synonym More Synonyms

 n-Butyl β-D-fructofuranoside Biological Activity

Description n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research[1].
Related Catalog
Target

Bax

Bcl-2

In Vitro n-Butyl-β-D-fructofuranoside (0-23.6 μg/mL; 24-78 hours) has antiproliferation activity and inhibits the viability of Bel-7402 cells[1]. n-Butyl-β-D-fructofuranoside (0-75 μg/mL; 0-72 hours) inhibits BEL-7402 cells by interfering with cell cycle and inducing apoptosis[1]. Cell Viability Assay[1] Cell Line: Bel-7402 cells Concentration: 0.47, 2.95, 5.90, 11.8, 17.7 and 23.6 μg/mL Incubation Time: 24, 48 and 72 hours Result: Inhibited the proliferation of Bel-7402 cells at both time- and dose-dependent manner. Cell Cycle Analysis[1] Cell Line: Bel-7402 cells Concentration: 0, 50 and 75 μg/mL Incubation Time: 24, 48 and 72 hours Result: Induced cell cycle arrest at G0/G1 phase. Western Blot Analysis[1] Cell Line: Bel-7402 cells Concentration: 23.6 μg/mL Incubation Time: 0, 24, 48 and 72 hours Result: Decreased Bcl-2 and increased Bax and p53 levels in a time manner.
References

[1]. Lu P, et, al. Antiproliferative effects of n-butyl-β-D-fructofuranoside from Kangaisan on Bel-7402 cells. Indian J Pharmacol. 2014 Jan-Feb;46(1):69-75. doi: 10.4103/0253-7613.125175.

 Chemical & Physical Properties

Molecular Formula C10H20O6
Molecular Weight 236.26200
Exact Mass 236.12600
PSA 99.38000

 Synonyms

Butyl fructofuranoside
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