Phenosafranine

Modify Date: 2024-01-04 19:43:05

Phenosafranine structure	Common Name	Phenosafranine
	CAS Number	81-93-6	Molecular Weight	322.792
	Density	1.1738 (rough estimate)	Boiling Point	478.49°C (rough estimate)
	Molecular Formula	C₁₈H₁₅ClN₄	Melting Point	300ºC
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of Phenosafranine

Phenosafranine is a phenazine dye. Phenosafranine has high binding affinity to triplex RNA compared to the parent duplex form, binds through intercalation to both forms of RNA. Phenosafranine can be used for staining plant cells, determination of hemoglobin, dopamine, serotonin and so on[1][2][3].

Name	safranin O
Synonym	More Synonyms

Description	Phenosafranine is a phenazine dye. Phenosafranine has high binding affinity to triplex RNA compared to the parent duplex form, binds through intercalation to both forms of RNA. Phenosafranine can be used for staining plant cells, determination of hemoglobin, dopamine, serotonin and so on[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Widholm JM. The use of fluorescein diacetate and phenosafranine for determining viability of cultured plant cells. Stain Technol. 1972 Jul;47(4):189-94. [2]. Liu, W., et al. Characterization of Phenosafranine–Hemoglobin Interactions in Aqueous Solution. J Solution Chem 40, 231–246 (2011). [3]. Pradhan AB, et al. An overview on the interaction of phenazinium dye phenosafranine to RNA triple and double helices. Int J Biol Macromol. 2016 May;86:345-51.

Description

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Widholm JM. The use of fluorescein diacetate and phenosafranine for determining viability of cultured plant cells. Stain Technol. 1972 Jul;47(4):189-94.

[2]. Liu, W., et al. Characterization of Phenosafranine–Hemoglobin Interactions in Aqueous Solution. J Solution Chem 40, 231–246 (2011).

[3]. Pradhan AB, et al. An overview on the interaction of phenazinium dye phenosafranine to RNA triple and double helices. Int J Biol Macromol. 2016 May;86:345-51.

Density	1.1738 (rough estimate)
Boiling Point	478.49°C (rough estimate)
Melting Point	300ºC
Molecular Formula	C₁₈H₁₅ClN₄
Molecular Weight	322.792
Exact Mass	322.098511
PSA	68.81000
LogP	0.99550
Index of Refraction	1.6110 (estimate)

Phenosafranine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SG1630000

CHEMICAL NAME :: Phenazinium, 3,7-diamino-5-phenyl-, chloride

CAS REGISTRY NUMBER :: 81-93-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C18-H15-N4.Cl

MOLECULAR WEIGHT :: 322.82

WISWESSER LINE NOTATION :: T C666 BK INJ BR& EZ MZ &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :: Insect - Drosophila melanogaster

DOSE/DURATION :: 1000 ppm

REFERENCE :: AMNTA4 American Naturalist. (Univ. of Chicago Press, Journals Div., POB 37005, Chicago, IL 60637) V.1- 1867- Volume(issue)/page/year: 87,295,1953

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	SG1630000

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Interaction of Klebsiella K14 capsular polysaccharide with cationic dyes pinacyanol chloride, acridine orange and phenosafranin has been studied by spectrophotometric and spectrofluorometric technique...

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Phenazinium, 3,7-diamino-5-phenyl-, chloride (1:1)

Phenosafranin

3,7-diamino-5-phenyl phenazinium chloride

MFCD00036335

Phenosafranine

3,7-Diamino-5-phenylphenazin-5-ium chloride

EINECS 201-387-0

Phenosofranine

Safrinin B Extra

Phenosafrinine

Phenosofrinine

Schultz No. 958

Safranin B Extra

10-phenylphenazin-10-ium-2,8-diamine,chloride

Phenosafranine,chloride

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Phenosafranine
Price: ￥218.0/5g
Purity: 80.0%
Stocking Period: 1 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Phenosafranin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Phenosafranin
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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