SC 34301

Modify Date: 2024-01-07 17:00:22

SC 34301 Structure
SC 34301 structure
Common Name SC 34301
CAS Number 81026-63-3 Molecular Weight 380.51800
Density 1.092g/cm3 Boiling Point 490.2ºC at 760 mmHg
Molecular Formula C22H36O5 Melting Point N/A
MSDS N/A Flash Point 158.2ºC

 Use of SC 34301


SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice[1][2].

 Names

Name enisoprost
Synonym More Synonyms

 SC 34301 Biological Activity

Description SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice[1][2].
Related Catalog
In Vivo SC 34301 (200 µg/kg; p.o.; once a day for three days) 显着减少细菌移位并提高存活率[1]。 Animal Model: BALB/c mice (E. coli, burned)[1] Dosage: 200 µg/kg Administration: P.o.; once a day for three days Result: Significantly reduced the degree of bacterial translocation as measured by blood dpm counts, improved survival rate to 60% in burned mice.
References

[1]. Pollak R, et al. A trial of the prostaglandin E1 analogue, enisoprost, to reverse chronic cyclosporine-associated renal dysfunction. Am J Kidney Dis. 1992 Oct;20(4):336-41.  

[2]. Fukushima R, et al. The degree of bacterial translocation is a determinant factor for mortality after burn injury and is improved by prostaglandin analogs. Ann Surg. 1992 Oct;216(4):438-44; discussion 444-5.  

 Chemical & Physical Properties

Density 1.092g/cm3
Boiling Point 490.2ºC at 760 mmHg
Molecular Formula C22H36O5
Molecular Weight 380.51800
Flash Point 158.2ºC
Exact Mass 380.25600
PSA 83.83000
LogP 3.72960
Index of Refraction 1.536

 Synthetic Route

 Synonyms

Prosta-4,13-dien-1-oic acid,11,16-dihydroxy-16-methyl-9-oxo-,methyl ester,(4Z,11alpha,13E)-(+-)