SC 34301

Modify Date: 2025-08-25 08:23:14

SC 34301 structure	Common Name	SC 34301
	CAS Number	81026-63-3	Molecular Weight	380.51800
	Density	1.092g/cm3	Boiling Point	490.2ºC at 760 mmHg
	Molecular Formula	C₂₂H₃₆O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	158.2ºC

Use of SC 34301

SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice[1][2].

Name	enisoprost
Synonym	More Synonyms

Description	SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
In Vivo	SC 34301 (200 µg/kg; p.o.; once a day for three days) 显着减少细菌移位并提高存活率[1]。 Animal Model: BALB/c mice (E. coli, burned)[1] Dosage: 200 µg/kg Administration: P.o.; once a day for three days Result: Significantly reduced the degree of bacterial translocation as measured by blood dpm counts, improved survival rate to 60% in burned mice.
References	[1]. Pollak R, et al. A trial of the prostaglandin E1 analogue, enisoprost, to reverse chronic cyclosporine-associated renal dysfunction. Am J Kidney Dis. 1992 Oct;20(4):336-41. [2]. Fukushima R, et al. The degree of bacterial translocation is a determinant factor for mortality after burn injury and is improved by prostaglandin analogs. Ann Surg. 1992 Oct;216(4):438-44; discussion 444-5.

Density	1.092g/cm3
Boiling Point	490.2ºC at 760 mmHg
Molecular Formula	C₂₂H₃₆O₅
Molecular Weight	380.51800
Flash Point	158.2ºC
Exact Mass	380.25600
PSA	83.83000
LogP	3.72960
Index of Refraction	1.536
InChIKey	CIBHDGPIOICRGX-ZQCHCGQNSA-N
SMILES	CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCC=CCCC(=O)OC

Precursor 9
CAS#:78908-10-8 (+/-)-methyl 7-... CAS#:78908-09-5 (+/-)-methyl 7-... CAS#:1552-12-1 1,5-cyclooctadiene CAS#:132803-41-9 (Z)-7-((1S,2R)-...
CAS#:129814-44-4 (+/-)-methyl tr... CAS#:78908-11-9 (+/-)-methyl 7-... CAS#:66792-29-8 (E)-trimethyl[[... CAS#:66792-28-7 trimethyl(4-met...
CAS#:62555-05-9 (1E)-(4R)-4-tri...
DownStream 0

Name: Relative gastric antisecretory effect in histamine-stimulated Heidenhain Pouch (HP) d...
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL672828

Name: Ratio of ED50 value of diarrheal effect to that of ED50 value of antisecretory effect
Source: ChEMBL
Target: N/A
External Id: CHEMBL851310

Name: Ratio of ED50 of diarrheal effect to antisecretory effect
Source: ChEMBL
Target: N/A
External Id: CHEMBL851137

Name: Antisecretory activity after iv administration in histamine-stimulated Heidenhain pou...
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL884427

Name: Activity for diarrheagenic effect in rats by intragastric administration and the valu...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL779796

Name: Diarrheal effect after ig administration in rats
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL780962

Name: Compound was evaluated for diarrheagenic side effects in adult male rats by intragast...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL783762

Name: Activity for gastric antisecretory activity in dogs by intrapouch administration and ...
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL669710

Name: Oral gastric antisecretory effect in histamine-stimulated Heidenhain Pouch (HP) dogs
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL671105

Name: Selectivity ratio was evaluated by the quotient of diarrheal ED50 value divided by an...
Source: ChEMBL
Target: N/A
External Id: CHEMBL847410

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Prosta-4,13-dien-1-oic acid,11,16-dihydroxy-16-methyl-9-oxo-,methyl ester,(4Z,11alpha,13E)-(+-)

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ENISOPROST
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.