(-)-MDO-NPA HCl

Modify Date: 2024-01-09 22:15:50

(-)-MDO-NPA HCl Structure
(-)-MDO-NPA HCl structure
Common Name (-)-MDO-NPA HCl
CAS Number 81264-57-5 Molecular Weight 307.38600
Density 1.209g/cm3 Boiling Point 456ºC at 760 mmHg
Molecular Formula C20H21NO2 Melting Point 250-252ºC
MSDS USA Flash Point 165.2ºC

 Use of (-)-MDO-NPA HCl


(-)-MDO-NPA HCl is an orally effective long-acting agent active at central dopamine receptors, and analogous aporphines.

 Names

Name (6aR)-7-Propyl-6a,7,8,9-tetrahydro-6H-benzo[de][1,3]benzodioxolo[ 4,5-g]quinoline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.209g/cm3
Boiling Point 456ºC at 760 mmHg
Melting Point 250-252ºC
Molecular Formula C20H21NO2
Molecular Weight 307.38600
Flash Point 165.2ºC
Exact Mass 307.15700
PSA 21.70000
LogP 3.88550
Index of Refraction 1.622

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~92%

(-)-MDO-NPA HCl Structure

(-)-MDO-NPA HCl

CAS#:81264-57-5

Literature: Ram, Vishnu J.; Neumeyer, John L. Journal of Organic Chemistry, 1981 , vol. 46, # 13 p. 2830 - 2831

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(-)-MDO-NPA HCl Structure

(-)-MDO-NPA HCl

CAS#:81264-57-5

Literature: Ram, Vishnu J.; Neumeyer, John L. Journal of Organic Chemistry, 1981 , vol. 46, # 13 p. 2830 - 2831

~%

(-)-MDO-NPA HCl Structure

(-)-MDO-NPA HCl

CAS#:81264-57-5

Literature: Ram, Vishnu J.; Neumeyer, John L. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 947 - 949

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(-)-MDO-NPA HCl Structure

(-)-MDO-NPA HCl

CAS#:81264-57-5

Literature: Ram, Vishnu J.; Neumeyer, John L. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 947 - 949

~%

(-)-MDO-NPA HCl Structure

(-)-MDO-NPA HCl

CAS#:81264-57-5

Literature: Ram, Vishnu J.; Neumeyer, John L. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 947 - 949

~%

(-)-MDO-NPA HCl Structure

(-)-MDO-NPA HCl

CAS#:81264-57-5

Literature: Ram, Vishnu J.; Neumeyer, John L. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 947 - 949

 Articles8

More Articles
Behavioral effects of (-)10,11-methylenedioxy-N-n-propylnoraporphine, an orally effective long-acting agent active at central dopamine receptors, and analogous aporphines.

Neuropharmacology 21(10) , 953-61, (1982)

Substituted and unsubstituted 10,11-methylenedioxy derivatives of apomorphine (APO) or its N-propyl congener (NPA) were synthesized and evaluated for their ability to alter motor activity or to induce...

Dopaminergic stimulation of oxytocin concentrations in the plasma of male and female monkeys by apomorphine and a D2 receptor agonist.

J. Clin. Endocrinol. Metab. 75(3) , 855-60, (1992)

Administration of the dopamine receptor agonist apomorphine causes a dose-dependent increase in plasma oxytocin concentrations and dose-specific behavioral changes in rodents. To investigate whether d...

Tissue levels of N-n-propylnorapomorphine after treatment with (-)10,11-methylenedioxy-N-n-propylnoraporphine, an orally long-acting prodrug active at central dopamine receptors.

Neuropharmacology 21(12) , 1311-6, (1982)

High performance liquid chromatography with electrochemical detection was used to assay N-n-propylnorapomorphine (NPA) and other aporphines. Pretreatment of rats with (-)10,11-methylenedioxy-N-n-propy...

 Synonyms

(R)-MDO-NPA
(S)-Propane-1,2-diamine dihydrochloride
R-(-)-1,2-propanediamine dihydrochloride
(S)-1,2-diaminopropane
(S)-diaminopropane dihydrochloride
R(-)-10,11-Methylenedioxy-N-(n-propyl)noraporphine
(S)-1,2-propanediamine*2HCl
(S)-1,2-Diaminopropane 2HCl
S-(-)-1,2-diaminopropane dihydrochloride
(S)-1,2-Propanediamine dihydrochloride
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