(Trifluoromethyl)trimethylsilane

Modify Date: 2025-08-23 15:36:28

(Trifluoromethyl)trimethylsilane structure	Common Name	(Trifluoromethyl)trimethylsilane
	CAS Number	81290-20-2	Molecular Weight	142.19
	Density	1.0±0.1 g/cm3	Boiling Point	49.3±40.0 °C at 760 mmHg
	Molecular Formula	C₄H₉F₃Si	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	-16.4±27.3 °C
	Symbol	GHS02	Signal Word	Danger

Use of (Trifluoromethyl)trimethylsilane

Trimethylsilyl(trifluoromethyl)silane is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Name	(Trifluoromethyl)trimethylsilane
Synonym	More Synonyms

Description	Trimethylsilyl(trifluoromethyl)silane is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	(Trifluoromethyl)trimethylsilane 被用作亲电底物三氟甲基化的有价值试剂。它还用于三氟甲基对醛和酮的亲核加成。它与催化量的 F-（TBAF 或 CsF）生成三氟甲基，并与羰基化合物反应生成三氟甲基化醇。

Density	1.0±0.1 g/cm3
Boiling Point	49.3±40.0 °C at 760 mmHg
Molecular Formula	C₄H₉F₃Si
Molecular Weight	142.19
Flash Point	-16.4±27.3 °C
Exact Mass	142.042557
LogP	1.85
Vapour Pressure	313.6±0.1 mmHg at 25°C
Index of Refraction	1.328
Storage condition	2-8°C

(Trifluoromethyl)trimethylsilane MSDS(Chinese)

Symbol	GHS02
Signal Word	Danger
Hazard Statements	H225
Supplemental HS	May form explosive peroxides.
Precautionary Statements	P210
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
Hazard Codes	F:Flammable;Xi:Irritant;
Risk Phrases	R11;R19;R36/37
Safety Phrases	S16-S33-S39-S26-S36-S29
RIDADR	UN 1993 3/PG 2
WGK Germany	3
Packaging Group	II
Hazard Class	3
HS Code	2931900090

Precursor 10
CAS#:75-77-4 Chlorotrimethyl... CAS#:75-46-7 Trifluoromethane CAS#:2314-97-8 Iodotrifluoromethane CAS#:75-63-8 Bromotrifluorom...
CAS#:426-58-4 Phenyl Trifluor... CAS#:703-18-4 Phenyl Trifluor... CAS#:400-53-3 Trimethylsilyl ... CAS#:421-82-9 Trifluoro(metha...
CAS#:456-56-4 ((trifluorometh... CAS#:75-16-1 METHYLMAGNESIUM...
DownStream 10
CAS#:1057657-62-1 1-(2-chloropyri... CAS#:107018-37-1 Benzonitrile, 4... CAS#:107040-75-5 2,2,2-Trifluoro... CAS#:111727-06-1 1-nitro-3-(3,3,...
CAS#:447-60-9 2-(Trifluoromet... CAS#:384-22-5 1-Nitro-2-(trif... CAS#:461-17-6 1,1,1-Trifluoro... CAS#:1524-26-1 1,1,1-TRIFLUORO...
CAS#:66711-82-8 1,1,1,5,5,5-Hex... CAS#:455-14-1 4-Aminobenzotri...

HS Code	2931900090
Summary	2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Facile synthesis of TMS-protected trifluoromethylated alcohols using trifluoromethyltrimethylsilane (TMSCF3) and various nucleophilic catalysts in DMF.

J. Org. Chem. 71 , 6806, (2006)

Organofluorine compounds are becoming increasingly important in different fields, such as material science, agro chemistry, and the pharmaceutical industry. Nucleophilic trifluoromethylation is one of...

Silane, trimethyl(trifluoromethyl)-

(trifluoromethyl)-trimethylsilane

Trifluoromethyl(trimethyl)silane

Trimethyl(trifluoromethyl)silane

(Trifluoromethyl)trimethylsilane

MFCD00145454