HUMAN M-CSF structure 
             | 
        Common Name | HUMAN M-CSF | ||
|---|---|---|---|---|
| CAS Number | 81627-83-0 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
| Symbol | 
             
            
            GHS07  | 
        Signal Word | Warning | |
| Name | HUMAN M-CSF | 
|---|
| Appearance of Characters | lyophilized powder | 
|---|---|
| Storage condition | −20°C | 
| Symbol | 
                                    
                                     
                                    
                                    GHS07  | 
                            
|---|---|
| Signal Word | Warning | 
| Hazard Statements | H315-H319-H335 | 
| Precautionary Statements | P261-P305 + P351 + P338 | 
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves | 
| Hazard Codes | Xi | 
| Risk Phrases | 36/37/38 | 
| Safety Phrases | 22-24/25-26 | 
| RIDADR | NONH for all modes of transport | 
| WGK Germany | 3 | 
| RTECS | GI5500000 | 
| 
                                    
                                    G-CSF preferentially supports the generation of gut-homing Gr-1high macrophages in M-CSF-treated bone marrow cells.
                                    
                                    
                                     J. Leukoc. Biol. 96(4) , 549-61, (2014) The G-CSF is best known for its activity in the generation and activation of neutrophils. In addition, studies on G-CSF(-/-) or G-CSFR(-/-) mice and BMC cultures suggested a role of G-CSF in macrophag...  | 
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                                    ADAM17 limits the expression of CSF1R on murine hematopoietic progenitors.
                                    
                                    
                                     Exp. Hematol. 43(1) , 44-52.e1-3, (2015) All-lymphoid progenitors (ALPs) yield few myeloid cells in vivo, but readily generate such cells in vitro. The basis for this difference remains unknown. We hypothesized that ALPs limit responsiveness...  | 
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                                    M-CSF priming of osteoclast precursors can cause osteoclastogenesis-insensitivity, which can be prevented and overcome on bone.
                                    
                                    
                                     J. Cell Physiol. 230(1) , 210-25, (2015) Osteoclasts and macrophages share progenitors that must receive decisive lineage signals driving them into their respective differentiation routes. Macrophage colony stimulation factor M-CSF is a comm...  |