dinophysistoxin-1

Modify Date: 2025-08-25 10:53:28

dinophysistoxin-1 structure	Common Name	dinophysistoxin-1
	CAS Number	81720-10-7	Molecular Weight	819.02900
	Density	1.27g/cm3	Boiling Point	923.3ºC at 760 mmHg
	Molecular Formula	C₄₅H₇₀O₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	267.9ºC

Use of dinophysistoxin-1

Dinophysistoxin 1 (DTX 1, 35-methylokadaic acid) is a causative agent of diarrhetic shellfish poisoning. Dinophysistoxin 1 exerts tumor-promoting activity, serves as a skin irritant as well[1].

Name	9,10-deepithio-9,10-didehydro-35-methyl-acanthifolicin
Synonym	More Synonyms

Description	Dinophysistoxin 1 (DTX 1, 35-methylokadaic acid) is a causative agent of diarrhetic shellfish poisoning. Dinophysistoxin 1 exerts tumor-promoting activity, serves as a skin irritant as well[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Dinophysistoxin 1 抑制特定的 [3H] 冈田酸与小鼠表皮颗粒部分的结合[1]。
In Vivo	Dinophysistoxin 1 (5 μg/mouse; 涂抹在背部; 每周 2 次, 共 30 周) 导致 100 μg 7,12-二甲基苯蒽 (DMBA) 处理组的荷瘤小鼠比例增加[1]。
References	[1]. Fujiki H, et al. Diarrhetic shellfish toxin, dinophysistoxin-1, is a potent tumor promoter on mouse skin. Jpn J Cancer Res. 1988 Oct;79(10):1089-93.

Density	1.27g/cm3
Boiling Point	923.3ºC at 760 mmHg
Molecular Formula	C₄₅H₇₀O₁₃
Molecular Weight	819.02900
Flash Point	267.9ºC
Exact Mass	818.48200
PSA	182.83000
LogP	5.45960
Index of Refraction	1.581

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AA8227820

CHEMICAL NAME :: Acanthifolicin, 9,10-deepithio-9,10-didehydro-35-methyl-

CAS REGISTRY NUMBER :: 81720-10-7

LAST UPDATED :: 199706

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C45-H70-O13

MOLECULAR WEIGHT :: 819.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12 mg/kg/30W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

REFERENCE :: JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985- Volume(issue)/page/year: 79,1089,1988

9,10-deepithio-9,10-didehydro-35-methyl-acanthifolici

(35R)-9,45-Seco-10-demercapto-9,10-didehydro-35-methylacanthifolicin

DINOPHYSISTOXIN-I

35-methylokadaicacid

DTX1

OKADAIC ACID,35-METHYL

Acanthifolicin,9,10-deepithio-9,10-didehydro-35-methyl

DINOPHYSISTOXIN-1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Dinophysistoxin-1
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 9,10-DEEPITHIO-9,10-DIDEHYDRO-35-METHYL-ACANTHIFOLICIN
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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