3-phosphoglyceric acid

Modify Date: 2024-01-16 17:35:45

3-phosphoglyceric acid structure	Common Name	3-phosphoglyceric acid
	CAS Number	820-11-1	Molecular Weight	183.03300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃H₇O₇P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 3-phosphoglyceric acid

3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation.

Name	3-phosphoglyceric acid
Synonym	More Synonyms

Description	3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation.
In Vitro	3-Phosphoglyceric acid (400 µM; 24 hours; BMDMs) treatment enhances Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification is also reversed[1]. 3-Phosphoglyceric treatment significantly augmentes gene expression as well as H3K4me3 deposition of Spp1 in IL-4-stimulated macrophages[1]. In yeast, 3-Phosphoglyceric acid acts as a metabolic checkpoint for the formation of a multicomponent enzyme complex including serine metabolic enzymes and pyruvate kinase isoform 2 (PKM2) homologue, which senses both serine metabolism and glycolysis and regulates H3K4 methylation and histone phosphorylation[1]. RT-PCR[1] Cell Line: Bone marrow-derived macrophages (BMDMs) Concentration: 400 µM Incubation Time: 24 hours Result: Enhanced Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification was also reversed.
References	[1]. Zhang W, et al. The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation. J Exp Med. 2018 Dec 3;215(12):3180-3193.

Molecular Formula	C₃H₇O₇P
Molecular Weight	183.03300
Exact Mass	182.96900
PSA	142.59000

Precursor 0
DownStream 7
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D-3-phosphoglycerate

4gwk

3-phospho-D-glyceric acid

(2R)-2-hydroxy-3-phosphonatooxypropanoate

3-phospho-D-glycerate

D-glycerate-3-P

D-Glycerate 3-phosphate

3fjg

3-P-D-glycerate

3-phosphonato-D-glycerate

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 3-Phosphoglyceric acid
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-hydroxy-3-phosphonooxy-propanoic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-hydroxy-3-phosphonooxy-propanoic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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