12R-HETE

Modify Date: 2024-01-12 17:08:06

12R-HETE Structure
12R-HETE structure
Common Name 12R-HETE
CAS Number 82337-46-0 Molecular Weight 320.466
Density 1.0±0.1 g/cm3 Boiling Point 487.7±45.0 °C at 760 mmHg
Molecular Formula C20H32O3 Melting Point N/A
MSDS N/A Flash Point 262.8±25.2 °C

 Use of 12R-HETE


12(R)-HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits.

 Names

Name (12R)-12-hydroxyicosa-5,8,10,14-tetraenoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 487.7±45.0 °C at 760 mmHg
Molecular Formula C20H32O3
Molecular Weight 320.466
Flash Point 262.8±25.2 °C
Exact Mass 320.235138
PSA 57.53000
LogP 5.45
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.514

 Synthetic Route

 Synonyms

12R-HETE
12(R)-hydroxyeicosatetraenoic acid
12-hydroxyicosatetraenoic acid
5,8,10,14-Eicosatetraenoic acid, 12-hydroxy-, (5Z,8Z,10E,12R,14Z)-
(5Z,8Z,10E,12R,14Z)-12-hydroxy-5,8,10,14-eicosatetraenoic acid
12(R)-hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid
(5Z,8Z,10E,12R,14Z)-12-Hydroxy-5,8,10,14-icosatetraenoic acid
12(R)-hydroxy-5,8,14-cis-10-trans-eicosatetraenoic acid
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