​JOE

Modify Date: 2025-08-26 17:43:35

​JOE Structure
​JOE structure
Common Name ​JOE
CAS Number 82855-40-1 Molecular Weight 505.25800
Density N/A Boiling Point N/A
Molecular Formula C23H14Cl2O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ​JOE


JOE is a fluorescent dye and can be used as a fluorescent label in DNA sequencing, PCR, and LCR amplifications. JOE possesses an absorbance of 525 nm and an emission of 550 nm[1].

 Names

Name 4',5'-dichloro-3',6'-dihydroxy-2',7'-dimethoxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid
Synonym More Synonyms

 ​JOE Biological Activity

Description JOE is a fluorescent dye and can be used as a fluorescent label in DNA sequencing, PCR, and LCR amplifications. JOE possesses an absorbance of 525 nm and an emission of 550 nm[1].
Related Catalog
References

[1]. Tsybulsky DA, et al. 4',5'-Dichloro-2',7'-dimethoxy-5(6)-carboxyfluorescein (JOE): synthesis and spectral properties of oligonucleotide conjugates. J Org Chem. 2012 Jan 20;77(2):977-84.

 Chemical & Physical Properties

Molecular Formula C23H14Cl2O9
Molecular Weight 505.25800
Exact Mass 504.00100
PSA 131.75000
LogP 4.68800

 Synthetic Route

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​JOE Structure

​JOE

CAS#:82855-40-1

Literature: Tsybulsky, Dmitry A.; Kvach, Maksim V.; Stepanova, Irina A.; Korshun, Vladimir A.; Shmanai, Vadim V. Journal of Organic Chemistry, 2012 , vol. 77, # 2 p. 977 - 984

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​JOE Structure

​JOE

CAS#:82855-40-1

Literature: Tsybulsky, Dmitry A.; Kvach, Maksim V.; Stepanova, Irina A.; Korshun, Vladimir A.; Shmanai, Vadim V. Journal of Organic Chemistry, 2012 , vol. 77, # 2 p. 977 - 984

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

4',5'-dichloro-2',7'-dimethoxy-6-carboxyfluorescein
6-JOE
6-carboxy-4',5'-dichloro-2',7'-dimethoxyfluorescein
2'7'-dimethoxy-4'5'-dichloro-6-carboxyfluorescein
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