Levonordefrin;Corbadrine

Modify Date: 2025-08-20 18:37:38

Levonordefrin;Corbadrine Structure
Levonordefrin;Corbadrine structure
Common Name Levonordefrin;Corbadrine
CAS Number 829-74-3 Molecular Weight 183.20
Density 1.328g/cm3 Boiling Point 431.575ºC at 760 mmHg
Molecular Formula C9H13NO3 Melting Point 212-215ºC dec.
MSDS Chinese USA Flash Point 214.809ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Levonordefrin;Corbadrine


Levonordefrin, a common alternative to levoepinephrine as a vasoconstrictor in dental local anesthetic preparations, is usually used in fivefold higher concentrations. Levonordefrin is generally considered equivalent to epinephrine[1].

 Names

Name (-)-3,4-Dihydroxynorephedrine
Synonym More Synonyms

 Levonordefrin;Corbadrine Biological Activity

Description Levonordefrin, a common alternative to levoepinephrine as a vasoconstrictor in dental local anesthetic preparations, is usually used in fivefold higher concentrations. Levonordefrin is generally considered equivalent to epinephrine[1].
Related Catalog
References

[1]. Robertson VJ, et al. Quantitative and qualitative analysis of the pressor effects of levonordefrin.

 Chemical & Physical Properties

Density 1.328g/cm3
Boiling Point 431.575ºC at 760 mmHg
Melting Point 212-215ºC dec.
Molecular Formula C9H13NO3
Molecular Weight 183.20
Flash Point 214.809ºC
Exact Mass 183.09000
PSA 86.71000
LogP 1.17870
Index of Refraction 1.633

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302 + H312 + H332-H315-H319-H335
Precautionary Statements P261-P280-P301 + P312 + P330-P305 + P351 + P338
Hazard Codes Xn: Harmful;
Risk Phrases R20/21/22;R36/37/38
Safety Phrases S26-S36
RIDADR UN 2811 6.1 / PGII
HS Code 2922509090

 Synthetic Route

~%

Levonordefrin;Corbadrine Structure

Levonordefrin;C...

CAS#:829-74-3

Literature: DE639126 , ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 23, p. 481

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol
LEVONORDEFRIN
1(S),2(R)-(+)-nordefrin
MFCD00134415
(-)-Nordefrin
Neo-cobefrin
Levonordefrin Base
Levonordefrin (200 mg)
D-(-)-Cobefrin
l-Cobefrin
BA 2818
CORBADRINE
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