Skimmianin
Skimmianin structure
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Common Name | Skimmianin | ||
|---|---|---|---|---|
| CAS Number | 83-95-4 | Molecular Weight | 259.257 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 401.6±40.0 °C at 760 mmHg | |
| Molecular Formula | C14H13NO4 | Melting Point | 178° | |
| MSDS | N/A | Flash Point | 196.7±27.3 °C | |
Use of SkimmianinSkimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with analgesic, antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4,7,8-trimethoxyfuro[2,3-b]quinoline |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with analgesic, antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 401.6±40.0 °C at 760 mmHg |
| Melting Point | 178° |
| Molecular Formula | C14H13NO4 |
| Molecular Weight | 259.257 |
| Flash Point | 196.7±27.3 °C |
| Exact Mass | 259.084473 |
| PSA | 53.72000 |
| LogP | 2.86 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.621 |
| InChIKey | SLSIBLKBHNKZTB-UHFFFAOYSA-N |
| SMILES | COc1ccc2c(OC)c3ccoc3nc2c1OC |
| Storage condition | 2-8C |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2934999090 |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Skimmianin CAS#:83-95-4 |
| Literature: Boyd, Derek R.; Sharma, Narain D.; O'Dowd, Colin R.; Carroll, Jonathan G.; Loke, Pui L.; Allen, Christopher C. R. Chemical Communications, 2005 , # 31 p. 3989 - 3991 |
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Skimmianin CAS#:83-95-4 |
| Literature: Boyd, Derek R.; Sharma, Narain D.; O'Dowd, Colin R.; Carroll, Jonathan G.; Loke, Pui L.; Allen, Christopher C. R. Chemical Communications, 2005 , # 31 p. 3989 - 3991 |
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Skimmianin CAS#:83-95-4 |
| Literature: Australian Journal of Chemistry, , vol. 7, p. 87,93 |
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Skimmianin CAS#:83-95-4 |
| Literature: Chemical Communications, , # 31 p. 3989 - 3991 |
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Skimmianin CAS#:83-95-4 |
| Literature: Australian Journal of Chemistry, , vol. 7, p. 87,93 |
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Skimmianin CAS#:83-95-4 |
| Literature: Chemical Communications, , # 31 p. 3989 - 3991 |
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Skimmianin CAS#:83-95-4 |
| Literature: Chemistry of Natural Compounds, , vol. 12, p. 709 - 713 Khimiya Prirodnykh Soedinenii, , vol. 12, # 6 p. 791 - 796 |
![4-methoxyfuro[2,3-b]quinoline-7,8-diol structure](https://image.chemsrc.com/caspic/121/119188-51-1.png)
![4-chloro-7,8-dimethoxyfuro[2,3-b]quinoline structure](https://image.chemsrc.com/caspic/204/865878-27-9.png)
![4,7-dimethoxyfuro[2,3-b]quinolin-8-ol structure](https://image.chemsrc.com/caspic/261/62580-17-0.png)
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 7 | |
|---|---|
| DownStream 3 | |
CAS#:23417-92-7![4,7-dimethoxy-8-(3-methylbut-2-enoxy)furo[2,3-b]quinoline structure](https://image.chemsrc.com/caspic/224/81536-07-4.png)
CAS#:81536-07-4This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| skimmiamine |
| 7,8-Dimethoxydictamnine |
| Skimmianine |
| b-fagarine |
| β-Fagarine |
| Chloroxylonine |
| 4,7,8-Trimethoxyfuro[2,3-b]quinoline |
| Skimmianin |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of 4,7,8-trimethoxyfuro[2,3-b]quinoline? |
| A: Main uses of 4,7,8-trimethoxyfuro[2,3-b]quinoline: Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with analgesic, antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. |
| Q: What is the SMILES notation of 4,7,8-trimethoxyfuro[2,3-b]quinoline? |
| A: SMILES notation of 4,7,8-trimethoxyfuro[2,3-b]quinoline is COc1ccc2c(OC)c3ccoc3nc2c1OC. |
| Q: What are the upstream materials of 4,7,8-trimethoxyfuro[2,3-b]quinoline? |
| A: Related upstream materials(CAS) of 4,7,8-trimethoxyfuro[2,3-b]quinoline: 186581-53-3;865878-27-9;124-41-4;110548-95-3;5876-17-5;77-78-1;62580-17-0. |
| Q: What is the InChIKey of 4,7,8-trimethoxyfuro[2,3-b]quinoline? |
| A: InChIKey of 4,7,8-trimethoxyfuro[2,3-b]quinoline is SLSIBLKBHNKZTB-UHFFFAOYSA-N. |
| Q: What is the molecular weight of 4,7,8-trimethoxyfuro[2,3-b]quinoline? |
| A: Molecular weight of 4,7,8-trimethoxyfuro[2,3-b]quinoline is 259.257. |
| Q: What is the polar surface area (PSA) of 4,7,8-trimethoxyfuro[2,3-b]quinoline? |
| A: Polar surface area (PSA) of 4,7,8-trimethoxyfuro[2,3-b]quinoline is 53.72000. |
| Q: What English synonyms does 4,7,8-trimethoxyfuro[2,3-b]quinoline have? |
| A: English synonyms of 4,7,8-trimethoxyfuro[2,3-b]quinoline: skimmiamine, 7,8-Dimethoxydictamnine, Skimmianine, b-fagarine, β-Fagarine, Chloroxylonine, 4,7,8-Trimethoxyfuro[2,3-b]quinoline, Skimmianin. |
| Q: What is the English name of 4,7,8-trimethoxyfuro[2,3-b]quinoline? |
| A: The English name of 4,7,8-trimethoxyfuro[2,3-b]quinoline is 4,7,8-trimethoxyfuro[2,3-b]quinoline. |
| Q: What are the downstream products of 4,7,8-trimethoxyfuro[2,3-b]quinoline? |
| A: Related downstream products(CAS) of 4,7,8-trimethoxyfuro[2,3-b]quinoline: 23417-92-7;81536-07-4;5876-17-5. |
| Q: What is the CAS number of 4,7,8-trimethoxyfuro[2,3-b]quinoline? |
| A: CAS number of 4,7,8-trimethoxyfuro[2,3-b]quinoline is 83-95-4. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |
| naturewill |