4-chloro-2,8-di(trifluoromethyl)quinoline
4-chloro-2,8-di(trifluoromethyl)quinoline structure
|
Common Name | 4-chloro-2,8-di(trifluoromethyl)quinoline | ||
|---|---|---|---|---|
| CAS Number | 83012-13-9 | Molecular Weight | 299.600 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 251.8±35.0 °C at 760 mmHg | |
| Molecular Formula | C11H4ClF6N | Melting Point | 46-48 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 106.1±25.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 251.8±35.0 °C at 760 mmHg |
| Melting Point | 46-48 °C(lit.) |
| Molecular Formula | C11H4ClF6N |
| Molecular Weight | 299.600 |
| Flash Point | 106.1±25.9 °C |
| Exact Mass | 298.993652 |
| PSA | 12.89000 |
| LogP | 4.36 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.495 |
| InChIKey | ZSQOESPYYNJBCZ-UHFFFAOYSA-N |
| SMILES | FC(F)(F)c1cc(Cl)c2cccc(C(F)(F)F)c2n1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933499090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
|
~85%
4-chloro-2,8-di... CAS#:83012-13-9 |
| Literature: Adam, Solange Tetrahedron, 1991 , vol. 47, # 36 p. 7609 - 7614 |
|
~57%
4-chloro-2,8-di... CAS#:83012-13-9 |
| Literature: Babu, Konda Ramesh; Eeshwaraiah, Begari; Aravind, Dachepally; Meshram, Harshadas M.; Raju, Rallabaldi Madhusudan; Bhattacharya, Apurba; Bandichhor, Rakeshwar Monatshefte fur Chemie, 2008 , vol. 139, # 2 p. 179 - 181 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 1 | |
|---|---|
| DownStream 2 | |
![bis[2,8-di(trifluoromethyl)quinolin-4-yl-2-pyridyl] ketone structure](https://image.chemsrc.com/caspic/345/35853-55-5.png)
CAS#:35853-55-5
CAS#:83012-12-8This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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New quinoline derivatives: synthesis and investigation of antibacterial and antituberculosis properties.
Eur. J. Med. Chem. 45 , 3374, (2010) Four new series of quinoline derivatives were synthesized starting from 2-trifluoromethyl aniline through multi-step reactions. In the reaction sequence, substituted aniline was cyclized to 4-hydroxy ... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-chloro-2,8-di(trifluoromethyl)quinoline |
| 4-Chloro-2,8-bis(trifluoromethyl)quinoline |
| EINECS 280-132-5 |
| MFCD00075104 |
| 4-Chloro-2,8-bis-trifluoromethyl-quinoline |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline? |
| A: Molecular weight of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline is 299.600. |
| Q: What is the polar surface area (PSA) of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline? |
| A: Polar surface area (PSA) of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline is 12.89000. |
| Q: What is the melting point of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline? |
| A: Melting point of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline is 46-48 °C(lit.). |
| Q: What is the SMILES notation of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline? |
| A: SMILES notation of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline is FC(F)(F)c1cc(Cl)c2cccc(C(F)(F)F)c2n1. |
| Q: What is the boiling point of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline? |
| A: Boiling point of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline is 251.8±35.0 °C at 760 mmHg. |
| Q: What is the English name of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline? |
| A: The English name of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline is 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline. |
| Q: What is the LogP of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline? |
| A: LogP of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline is 4.36. |
| Q: What is the InChIKey of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline? |
| A: InChIKey of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline is ZSQOESPYYNJBCZ-UHFFFAOYSA-N. |
| Q: What are the downstream products of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline? |
| A: Related downstream products(CAS) of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline: 35853-55-5;83012-12-8. |
| Q: What English synonyms does 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline have? |
| A: English synonyms of 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline: 4-chloro-2,8-di(trifluoromethyl)quinoline, 4-Chloro-2,8-bis(trifluoromethyl)quinoline, EINECS 280-132-5, MFCD00075104, 4-Chloro-2,8-bis-trifluoromethyl-quinoline. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |