4-chloro-2,8-di(trifluoromethyl)quinoline

Modify Date: 2024-01-02 23:53:05

4-chloro-2,8-di(trifluoromethyl)quinoline Structure
4-chloro-2,8-di(trifluoromethyl)quinoline structure
Common Name 4-chloro-2,8-di(trifluoromethyl)quinoline
CAS Number 83012-13-9 Molecular Weight 299.600
Density 1.5±0.1 g/cm3 Boiling Point 251.8±35.0 °C at 760 mmHg
Molecular Formula C11H4ClF6N Melting Point 46-48 °C(lit.)
MSDS Chinese USA Flash Point 106.1±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2,8-Bis(Trifluoromethyl)-4-Chloroquinoline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 251.8±35.0 °C at 760 mmHg
Melting Point 46-48 °C(lit.)
Molecular Formula C11H4ClF6N
Molecular Weight 299.600
Flash Point 106.1±25.9 °C
Exact Mass 298.993652
PSA 12.89000
LogP 4.36
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.495

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933499090

 Synthetic Route

~85%

4-chloro-2,8-di(trifluoromethyl)quinoline Structure

4-chloro-2,8-di...

CAS#:83012-13-9

Literature: Adam, Solange Tetrahedron, 1991 , vol. 47, # 36 p. 7609 - 7614

~57%

4-chloro-2,8-di(trifluoromethyl)quinoline Structure

4-chloro-2,8-di...

CAS#:83012-13-9

Literature: Babu, Konda Ramesh; Eeshwaraiah, Begari; Aravind, Dachepally; Meshram, Harshadas M.; Raju, Rallabaldi Madhusudan; Bhattacharya, Apurba; Bandichhor, Rakeshwar Monatshefte fur Chemie, 2008 , vol. 139, # 2 p. 179 - 181

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
New quinoline derivatives: synthesis and investigation of antibacterial and antituberculosis properties.

Eur. J. Med. Chem. 45 , 3374, (2010)

Four new series of quinoline derivatives were synthesized starting from 2-trifluoromethyl aniline through multi-step reactions. In the reaction sequence, substituted aniline was cyclized to 4-hydroxy ...

 Synonyms

4-chloro-2,8-di(trifluoromethyl)quinoline
4-Chloro-2,8-bis(trifluoromethyl)quinoline
EINECS 280-132-5
MFCD00075104
4-Chloro-2,8-bis-trifluoromethyl-quinoline
Quinoline, 4-chloro-2,8-bis(trifluoromethyl)-
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